Results 81 to 90 of about 5,282,350 (229)

Photodynamic therapy in a patient with perianal extramammary Paget's disease

Extramammary Paget's disease is a rare neoplasm of apocrine gland-bearing areas of the skin. One of the most common localizations of such a tumor is the perianal area. Surgery is the most frequently reported therapy.
Grigorievykh N., Ivanova-Radkevich V., Kaprin A., Filonenko E., Volchenko N.   +4 more
core   +1 more source

Perianal Paget's Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Perianal Paget's disease is rare and may be secondary to an underlying anorectal adenocarcinoma. Full‐thickness biopsy with immunohistochemistry is key to distinguish primary from secondary disease and to guide staging. Wide local excision is standard, while radiotherapy is a reasonable option when radical surgery is declined.
Daniela Lira, Maria Reigota Miranda, Marta Serra, Margarida Martins, Júlio Alves, Joana Noronha   +5 more
wiley   +1 more source

Extramammary Paget’s disease of the scrotum

Journal of the Chinese Medical Association, 2011
Extramammary Paget's disease is an uncommon intra-epidermal malignant neoplasm that arises in area rich in apocrine glands. Common sites of occurrence include the vulva, perianal region, perineum, and scrotum. The lesion may be accompanied by an invasive adenocarcinoma or adenocarcinoma in situ of the apocrine glands.
Juang, Guang-Dar, Lin, Meng-Yan, Hwang, Thomas I-Sheng   +2 more
openaire   +2 more sources

The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget’s disease

Cell Research, 2020
Mammary and extramammary Paget’s Diseases (PD) are a malignant skin cancer characterized by the appearance of Paget cells. Although easily diagnosed, its pathogenesis remains unknown.
Yong-Li Song, C. Guerrero-Juarez, Zhongjian Chen, Yi-Chen Tang, Xiang-Hui Ma, Cong Lv, Xueyun Bi, Min Deng, Lina Bu, Yuhua Tian, Ruiqi Liu, Ran Zhao, Jiu-Zhi Xu, Xiao-Le Sheng, Sujuan Du, Ye-Qiang Liu, Yu Zhu, Shi-jun Shan, Hong-Duo Chen, Yi-Qiang Zhao, Guangbiao Zhou, Jian-Wei Shuai, F. Ren, L. Xue, Zhaoxia Ying, X. Dai, C. Lengner, B. Andersen, M. Plikus, Q. Nie, Zheng-Quan Yu   +30 more
semanticscholar   +1 more source

Extramammary Paget's disease with the appearance of a nodule: a case report [PDF]

, 2010
Background Extramammary Paget's disease (EMPD) remains a rare condition with only a limited number of cases reported in the literature. EMPD is mainly composed of intraepidermal Paget cells, and possesses variable clinical behaviors and ...
Xia Wang, Jian Yang, Wenlin Yang, Wang Xia, Yang Wenlin, Yang Jian   +5 more
core   +3 more sources

Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis

International Journal of Dermatology, Volume 65, Issue 3, Page 464-488, March 2026.
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla, Zseraldin Metyovinyi, Fanni Adél Meznerics, Arash Mirzahosseini, Judit Tőke, Miklós Tóth, Henriett Butz, Attila Patócs, Márta Medvecz   +8 more
wiley   +1 more source

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, Volume 13, Issue 2, 9 January 2026.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source

Long-Term Complete Response and Survival in Metastatic Extramammary Paget’s Disease Treated With Trastuzumab Plus Paclitaxel: A Case Report

Cureus
Extramammary Paget’s disease is a rare skin cancer that usually arises from the secretory cells of the apocrine glands. In most cases, an extramammary Paget’s tumor occurs as a single intraepithelial form not associated with another cancer, although ...
M. Chilelli, C. Signorelli, J. R. Giron Berrios, Armando Raso, F. Nelli, E. Ruggeri   +5 more
semanticscholar   +1 more source

Correspondence: Primary Cutaneous NUT Adnexal Carcinoma: A Case Report With Novel Clinical and Pathological Observations

Journal of Cutaneous Pathology, Volume 53, Issue 7, Page 622-623, July 2026.
Woo Cheal Cho
wiley   +1 more source