Results 81 to 90 of about 17,427 (222)

Clinical Characteristics, Treatment, and Prognostic Factors of Patients With Primary Extramammary Paget's Disease (EMPD): A Retrospective Analysis of 44 Patients From a Single Center and an Analysis of Data From the Surveillance, Epidemiology, and End Results (SEER) Database

Frontiers in Oncology, 2020
Objective: Primary extramammary Paget's disease (EMPD) is a rare cutaneous malignancy. The aim of this article is to analyze clinical characteristics, evidence of the prognosis, and share treatment experience of primary EMPD.
Shanshan Weng, N. Zhu, Dan Li, Yurong Chen, Yinuo Tan, Jiaqi Chen, Ying Yuan   +6 more
semanticscholar   +1 more source

Comprehensive management of vulvovaginal cancers

CA: A Cancer Journal for Clinicians, Volume 75, Issue 5, Page 410-435, September/October 2025.
Abstract Vulvar and vaginal cancers represent rare malignancies, with an incidence of 2.7 per 100,000 women for vulvar cancer, predominantly affecting women older than 60 years, although rising rates are observed in younger demographics. Approximately 90% of vulvar cancers are squamous cell carcinoma and frequently are associated with human ...
Angélica Nogueira‐Rodrigues, Maaike H. M. Oonk, Domenica Lorusso, Brian Slomovitz, Mario M. Leitão Jr, Glauco Baiocchi   +5 more
wiley   +1 more source

Cancer of the vulva: 2025 update

International Journal of Gynecology &Obstetrics, Volume 171, Issue S1, Page 36-47, September 2025.
Abstract Vulvar cancer is an uncommon gynecological malignancy primarily affecting postmenopausal women. No specific screening exists and the most effective strategy to reduce the incidence of vulvar cancer is the opportune treatment of predisposing and preneoplastic lesions associated with its development.
Alexander B. Olawaiye, Mauricio A. Cuello, Sushil Beriwal, Linda J. Rogers   +3 more
wiley   +1 more source

Genital Psoriasis: Shining Light on This Hidden Disease

JEADV Clinical Practice, Volume 4, Issue 4, Page 719-731, September 2025.
Psoriasis occurring on skin of the genital and perigenital regions has specific diagnostic and treatment requirements due to the sensitivity and private nature of these areas. A multidisciplinary group of experts in the management of genital psoriasis, the Genital Psoriasis Wellness Consortium, convened to discuss the impact of genital psoriasis on ...
Jennifer Cather, Melodie Young, Muriel Boreham, Shehla Admani, Tina Bhutani, Erin Foster, Richard Fried, Melinda Gooderham, Jeannette Jakus, Sandra Johnson, Ryoichi Kamide, John Koo, Tiffany Mayo, Michael Payette, Caitriona Ryan, Lucinda Whitney, Krista Bohnert, Melissa Seal, Patrick Burnett, Diane Hanna   +19 more
wiley   +1 more source

Extramammary Paget's Disease: 20 years of Experience in Chinese Population [PDF]

, 2012
published_or_final_versio
Chan, YW, Chow, VLY, Chung, HP, Li, GKH
core  

asymmetrically pigmented patch on the vulvo perineal area a quiz [PDF]

, 2011
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M Le Donne, M Lentini
core   +1 more source

Human epidermal growth factor receptor-2 (HER2) is a potential therapeutic target in extramammary Paget’s disease of the vulva

International Journal of Gynecological Cancer, 2020
Background Invasive vulvar Paget’s disease with over-expression of the human epidermal growth factor receptor 2 (HER2) protein is potentially suitable for targeted therapy, especially in a metastatic setting where no effective treatments are available ...
M. Bartoletti, R. Mazzeo, Marco de Scordilli, A. Del Fabro, M. Vitale, L. Bortot, M. Nicoloso, S. Corsetti, M. Bonotto, S. Scalone, G. Giorda, R. Sorio, C. Andreetta, M. Meacci, R. de Vivo, G. Fasola, F. Sopracordevole, F. Puglisi   +17 more
semanticscholar   +1 more source

Improving imiquimod use in cervical high‐grade squamous intraepithelial lesions: A qualitative study

Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 9, Page 1712-1719, September 2025.
Adequate patient counselling on imiquimod treatment, including the possible application methods and potential side effects, along with optimal guidance during treatment, contributes to a better patient experience and reduces the likelihood of early discontinuation of treatment.
Caroline L. P. Muntinga, Helena C. J. Schellekens, Charlotte G. J. Penders, Hélène van Meir, Gatske M. Nieuwenhuyzen‐De Boer, Anna J. M. van de Sande, Heleen J. van Beekhuizen, Peggy J. de Vos Van Steenwijk, Ruud L. M. Bekkers, Edith M. G. van Esch   +9 more
wiley   +1 more source

CXCL13 and CCL21 Induce Tertiary Lymphoid Structures and Enhance the Efficacy of Immunotherapy for Melanoma

Cancer Science, Volume 116, Issue 8, Page 2075-2085, August 2025.
Plasma CCL21 levels were significantly increased in tertiary lymphoid structures (TLS)‐positive melanoma cases both before and after immune checkpoint inhibitors (ICI) treatment, while CXCL13 levels were significantly elevated after ICI treatment. We successfully induced TLS by co‐administering CXCL13 and CCL21 in a mouse melanoma model, clarifying ...
Maki Yoshimitsu, Motoki Nakamura, Shinji Kano, Tetsuya Magara, Hiroshi Kato, Aiko Sakai, Masaya Sugiyama, Masashi Mizokami, Akimichi Morita   +8 more
wiley   +1 more source