Results 51 to 60 of about 2,047 (196)

Single‐Center Epidemiological Analysis of Malignant Transformation With Skin Ulcers in Outpatients

International Wound Journal, Volume 23, Issue 1, January 2026.
ABSTRACT Investigate the epidemiological characteristics of outpatients initially diagnosed with skin ulcers who were ultimately confirmed to have cutaneous malignant tumours, and provide a diagnostic and therapeutic basis for the occurrence of secondary diseases in chronic wounds.
Yaoyao Kong, Haixia Wang, Nan Cao, Pengcheng Huai, Zhenzhen Wang, Chaoqi Zuo, Xueqing Wang, Yilei Wu, Yongxia Liu, Shengli Chen, Hong Liu, Guangliang Zhang   +11 more
wiley   +1 more source

First Case of Primary Breast Melanoma in Central America: Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Primary breast melanoma is an exceedingly rare neoplasm, accounting for < 0.5% of all malignant breast tumors. Its scarcity and highly variable clinical presentation often delay diagnosis and complicate management. We report the case of a 55‐year‐old woman with a primary non‐cutaneous melanoma of the right breast initially misdiagnosed as high‐
Ana García‐Urbina, Denis Espinoza‐Vásquez, Johanna Obregón‐Silva, Arlin Montoya Rodríguez   +3 more
wiley   +1 more source

Prostate carcinoma metastatic to the skin as an extrammamary Paget’s disease

Diagnostic Pathology, 2012
Aim The current paper describes a case of prostatic adenocarcinoma metastatic to the skin presenting as an extrammamary Paget's disease, a very rare and poorly characterised morphological entity. We report a case of prostatic carcinoma metastatic to skin
Petcu Eugen, Gonzalez-Serva Aldo, Wright Robert G, Slevin Mark, Brinzaniuc Klara   +4 more
doaj   +1 more source

Invasive Vulval Paget’s disease treated with primary radiotherapy: A rare case report and literature review

Gynecologic Oncology Reports, 2020
Extramammary Vulval Paget’s Disease (VPD) is rare neoplasm of post-menopausal women. In relatively young perimenopausal patients, it can cause both diagnostic dilemma and therapeutic challenges. Majority of VPD is of non-invasive variety.
Avir Sarkar, S.C. Saha, Pooja Sikka, Neha Kumari, Pranab Dey, Bhavana Rai   +5 more
doaj   +1 more source

Perianal Paget’s Disease in a Forty-Five-Year-Old Man and Review of the Literature [PDF]

Iranian Journal of Colorectal Research, 2015
Introduction Extramammary Paget’s disease is a rare neoplasm of the skin that might develop in perianal region. Although different management options are available, wide local excision is still the method of choice.
Yavar Shams Hojjati, Abbas Abdollahi, Ghodratollah Maddah, Asieh Sadat Fattahi   +3 more
doaj   +1 more source

About the Author

Клинический разбор в общей медицине, 2022
Extramammary Paget's disease (EMPD) is a rare variant of adenocarcinoma, the most common localization of which is a vulva. Clinical manifestations are nonspecific and can be initially diagnosed as manifestations of other dermatoses, which makes early ...
Yulia N. Grekova , Muza M. Kokhan , Igor A. Kuklin , Nina P. Toropova   +3 more
doaj   +1 more source

Programmed Death-Ligand 1 and Programmed Death-Ligand 2 Expression Can Affect Prognosis in Extramammary Paget’s Disease [PDF]

, 2021
Aya Kawaguchi, Jun Akiba, Reiichiro Kondo, Eiji Sadashima, Sachiko Ogasawara, Yoshiki Naito, Hironori Kusano, Sakiko Sanada, Ikko Muto, Takekuni Nakama, Hirohisa Yano   +10 more
openalex   +1 more source

Japanese Dermatological Association Guidelines: Clinical Questions of Guidelines for Merkel Cell Carcinoma 2025

The Journal of Dermatology, Volume 52, Issue 11, Page e954-e967, November 2025.
ABSTRACT Merkel cell carcinoma (MCC) is a highly malignant skin cancer characterized by high rates of recurrence and metastasis. Although rare, the incidence has noticeably increased in recent years. It is also known to be a highly immunogenic tumor, and the use of immune checkpoint inhibitors has begun for advanced cases.
Motoki Nakamura, Kotaro Nagase, Junji Kato, Masahito Yasuda, Natsuo Tomita, Tadahiro Kobayashi, Keitaro Fukuda, Akihiko Yuki, Hiroshi Uchi, Hiroshi Koga, Tomomitsu Miyagaki, Yasuhiro Nakamura   +11 more
wiley   +1 more source

Multiple Rare Primary Malignancies: A Mixed Squamous Neuroendocrine Adenocarcinoma of the Cervix, Metastasized Carcinosarcoma and Extramammary Vulvar Paget’s Disease Case Report

Medicina, 2023
The occurrence of more than one primary malignant tumor in a single patient is rare. Multiple primary malignancies can pose difficulties in differential diagnosis between primary tumors and metastasis. Here, we present a case report with multiple primary
Linas Andreika, Karolina Vankevičienė, Marija Plioplytė, Monika Bitinaitytė, Vilius Rudaitis   +4 more
doaj   +1 more source

An Evaluation of HER2 Expression Heterogeneity in Primary Tumors and Metastatic Lymph Nodes of Patients With Advanced Extramammary Paget's Disease: Prognostic and Therapeutic Implications

Cancer Medicine, Volume 14, Issue 19, October 2025.
ABSTRACT Background HER2 expression in primary versus metastatic tumors in advanced Extramammary Paget's Disease (EMPD) remains inadequately characterized. This investigation aimed to assess HER2 expression heterogeneity between primary tumors and metastatic lymph nodes (LNs) in patients with advanced EMPD and to assess the prognostic value of HER2 ...
Zhicheng Liu, Xingliang Tan, Zhiming Wu, Yi Tang, Qianghua Zhou, Wensu Wei, Cong Yang, Long Huang, Yanjun Wang, Kai Yao   +9 more
wiley   +1 more source