Results 71 to 80 of about 2,047 (196)

Trastuzumab monotherapy as maintenance treatment for metastatic HER2+ vulvar Paget disease: systematic review and case report [PDF]

Vulvar Paget's disease (VPD) is a rare intraepithelial malignancy frequently associated with HER2 overexpression. This study offers insights into managing HER2-positive extramammary Paget's disease cases in which trastuzumab monotherapy was administered ...
Berretta, Massimiliano, Canzonieri, Vincenzo, Foti, Roberta, Gelsomino, Claudia, Gulino, Ferdinando Antonio, Incognito, Dalila, Incognito, Giosuè Giordano, Palumbo, Marco, Picone, Antonio   +8 more
core   +1 more source

Successful Intra-Arterial Chemotherapy for Extramammary Paget’s Disease of the Axilla in a Patient with Parkinson’s Disease [PDF]

, 2009
Extramammary Paget’s disease (EMPD) is a rare intraepithelial neoplasm occurring less frequently in men and even more rarely in the axilla. A 59-year-old man with severe Parkinson’s disease presented with axillary EMPD.
A Urabe, AB Chagpar, AS Imai, B Damascelli, Bruno Damascelli, E Castelli, J Chanda, J Kanitakis, JD Zollo, M Coppens, R Andres, Vladimira Ticha   +11 more
core   +2 more sources

Curative Effect of Cutaneous Ulcer Wound Repair Through a Novel Liquid Dressing After HpD‐PDT Treatment of Extramammary Paget's Disease—A Prospective, Semi‐Lesion Controlled, Pilot Study

Journal of Cosmetic Dermatology, Volume 24, Issue 9, September 2025.
ABSTRACT Objective To evaluate the clinical efficacy and safety of a novel skin wound dressing in promoting the repair of the ulcer wound after the treatment of Extramammary Paget's Disease (EMPD) with Hematoporphyrin Derivative Photodynamic Therapy (HpD‐PDT).
Dixin Wang, Yan Zhao, Qihang Chang, Peiru Wang, Guolong Zhang, Xiuli Wang   +5 more
wiley   +1 more source

A Case of Secondary Extramammary Paget's Disease Surrounding a Cutaneous Ureterostoma After Recurrence of Bladder Urothelial Carcinoma

IJU Case Reports
Introduction Secondary extramammary Paget's disease features intraepidermal carcinoma caused by tumor invasion and migration into adjacent skin. Case Presentation A 68‐year‐old man underwent radical cystectomy and bilateral cutaneous ureterostomy for ...
Masahiro Mizoguchi, Ichiro Chihara, Keisuke Sano, Tomokazu Kimura, Shuya Kandori, Hiromitsu Negoro, Bryan J. Mathis, Hitomi Kawai, Daisuke Matsubara, Hiroyuki Nishiyama   +9 more
doaj   +1 more source

Extramammary Paget’s Disease Versus Lichen Sclerosus

Acta Medica Martiniana, 2016
Burning, itching and dyspareunia are typical symptoms of many genital diseases. These subjective complaints can be misdiagnosed because of different clinical presentations. We present a case report of a postmenopausal woman treated for genital warts over
Pappova T., Pec J., Kozarova A., Adamicova K.   +3 more
doaj   +1 more source

Reconstruction of the labia majora using a neurovascular pedicled pudendal thigh flap after extensive vulvectomy for primary extramammary Paget's disease: A case report

Clinical Case Reports, 2023
Key Clinical Message A neurovascular pedicled pudendal thigh flap was used to reconstruct labial defect after extensive vulvectomy for primary extramammary Paget's disease.
Jiangbo Cui, Yu Zhang, Zhou Yu, Xing Fan, Xi Zhang, Li Yang, Baoqiang Song, Yang Li   +7 more
doaj   +1 more source

The clinical evidence and the role of imiquimod in the extramammary Paget disease [PDF]

, 2014
Extramammary Paget disease is a rare disease. Different treatment options are used for its management, among them treatment with imiquimod. Our aim is to clarify the efficacy and safety of the use of topical imiquimod cream in the treatment of ...
Charalampos Karachalios, Christos Iavazzo, Fotinie Ntziora, Ioannis D. Gkegkes, Paraskevi Evangelia Iavazzo   +4 more
core   +1 more source

CXCL13 and CCL21 Induce Tertiary Lymphoid Structures and Enhance the Efficacy of Immunotherapy for Melanoma

Cancer Science, Volume 116, Issue 8, Page 2075-2085, August 2025.
Plasma CCL21 levels were significantly increased in tertiary lymphoid structures (TLS)‐positive melanoma cases both before and after immune checkpoint inhibitors (ICI) treatment, while CXCL13 levels were significantly elevated after ICI treatment. We successfully induced TLS by co‐administering CXCL13 and CCL21 in a mouse melanoma model, clarifying ...
Maki Yoshimitsu, Motoki Nakamura, Shinji Kano, Tetsuya Magara, Hiroshi Kato, Aiko Sakai, Masaya Sugiyama, Masashi Mizokami, Akimichi Morita   +8 more
wiley   +1 more source

Longstanding Perianal Ulcers

JEADV Clinical Practice, Volume 4, Issue 5, Page 1274-1277, December 2025.
Narachai Julanon, Thanaphon Anutraungkool, Sirawich Jessadapattarakul, Vincent Piguet   +3 more
wiley   +1 more source