Results 71 to 80 of about 2,223 (231)
Surgical Case Reports, 2018 Background Extramammary Paget’s disease (EMPD) of the esophagus is a rare tumor, with most cases originating from invasive adenocarcinoma of the esophagus.
Akihiko Sano +11 more
doaj +1 more source
A case of extramammary inguinal Paget disease in a male patient: surgical treatment with an abdominal advancement cutaneous flap [PDF]
, 2017 Extramammary Paget disease (EMPD) is a rare neoplasm. The clinical case of a 55-year-old man with a two-year history of a pruritic, painless erythematous skin rash on the inguinal region and scrotum is described.
Brandi, Cesare +7 more
core +1 more source
The Journal of Dermatology, Volume 52, Issue 11, Page e954-e967, November 2025.ABSTRACT Merkel cell carcinoma (MCC) is a highly malignant skin cancer characterized by high rates of recurrence and metastasis. Although rare, the incidence has noticeably increased in recent years. It is also known to be a highly immunogenic tumor, and the use of immune checkpoint inhibitors has begun for advanced cases.
Motoki Nakamura +11 more
wiley +1 more source
Comparison of the biomarkers for targeted therapies in primary extra-mammary and mammary Paget's disease. [PDF]
, 2020 Primary Extra-mammary Paget's disease (EMPD) is a very rare cutaneous adenocarcinoma affecting anogenital or axillary regions. It is characterized by a prolonged course with recurrences and eventually distant metastatic spread for which no specific ...
Choi, April +11 more
core +1 more source
Cancer Medicine, Volume 14, Issue 19, October 2025.ABSTRACT Background HER2 expression in primary versus metastatic tumors in advanced Extramammary Paget's Disease (EMPD) remains inadequately characterized. This investigation aimed to assess HER2 expression heterogeneity between primary tumors and metastatic lymph nodes (LNs) in patients with advanced EMPD and to assess the prognostic value of HER2 ...
Zhicheng Liu +9 more
wiley +1 more source
Serum Nectin‐4 as a Potential Prognostic Biomarker for Extramammary Paget Disease
Experimental Dermatology, Volume 34, Issue 10, October 2025.ABSTRACT Nectin cell adhesion molecule 4 (Nectin‐4) is overexpressed in the tissue of extramammary Paget disease (EMPD), and its potential role as a circulating biomarker remains poorly explored. We therefore investigated serum levels of Nectin‐4 in EMPD patients and healthy controls by ELISA assay and analysed its clinical relevance.
Hiromichi Morita +9 more
wiley +1 more source
Comprehensive management of vulvovaginal cancers
CA: A Cancer Journal for Clinicians, Volume 75, Issue 5, Page 410-435, September/October 2025.Abstract Vulvar and vaginal cancers represent rare malignancies, with an incidence of 2.7 per 100,000 women for vulvar cancer, predominantly affecting women older than 60 years, although rising rates are observed in younger demographics. Approximately 90% of vulvar cancers are squamous cell carcinoma and frequently are associated with human ...
Angélica Nogueira‐Rodrigues +5 more
wiley +1 more source
Cancer of the vulva: 2025 update
International Journal of Gynecology &Obstetrics, Volume 171, Issue S1, Page 36-47, September 2025.Abstract Vulvar cancer is an uncommon gynecological malignancy primarily affecting postmenopausal women. No specific screening exists and the most effective strategy to reduce the incidence of vulvar cancer is the opportune treatment of predisposing and preneoplastic lesions associated with its development.
Alexander B. Olawaiye +3 more
wiley +1 more source
Extramammary Paget's Disease: 20 years of Experience in Chinese Population [PDF]
, 2012 published_or_final_versio
Chan, YW, Chow, VLY, Chung, HP, Li, GKH
core
Acantholytic Anaplastic Extramammary Paget's Disease: A Case Report and Review of the Literature [PDF]
, 2011 Extramammary Paget's disease (EMPD) is an uncommon intraepithelial neoplasm that most commonly arises on the vulva and perianal region. Very few cases of EMPD revealing a histological Bowenoid appearance have been reported.
Bark-Lynn Lew +11 more
core +2 more sources