Results 41 to 50 of about 37,516 (275)

Mediastinal plasmocytoma with multiple myeloma: unusual presentation

PAMJ Clinical Medicine, 2020
We report a rare case about a 60 years old Moroccan woman with a past medical history of gastrointestinal tuberculosis, admitted to the emergency department with fever, coughing, weight loss, Spontaneous sternum fracture, back and chest pain.
Nouama Bouanani, Sophia Berrada
doaj   +1 more source

Endobronchial Mass: A Rare Manifestation of Multiple Solitary Plasmacytoma

Journal of the Belgian Society of Radiology, 2023
Multiple solitary plasmacytoma is the rare presentation of plasma cell neoplasm that can mimic multiple metastases. Primary endobronchial plasmacytoma is an extremely rare condition of extramedullary plasmacytoma.
Thanawat Anukanchanavera, Chayaporn Kaewsathorn Kaewsathorn, Nantaka Kiranantawat   +2 more
doaj   +1 more source

Therapeutic Silencing of Tmprss6 Reduces Iron‐Induced Inflammation and Prolongs Survival in MDS Mice

American Journal of Hematology, EarlyView.
ABSTRACT Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Despite advances in supportive and targeted therapies, disease‐modifying interventions remain limited.
Shahla Vilcassim, Nuttanan Pholngam, Rattanawan Thubthed, Tiwaporn Nualkaew, Saovaros Svasti, Pornthip Chaichompoo, Kai Kysenius, Peter J. Crouch, Sibylle Dames, Mona Eisermann, Alberto Martinez, Ute Schaeper, Jim Vadolas, George Grigoriadis   +13 more
wiley   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Extramedullary paravertebral mass: an unusual presentation of hairy cell leukaemia

European Journal of Case Reports in Internal Medicine
Background: Hairy cell leukaemia (HCL) is an uncommon, indolent, B-cell, lymphoproliferative disorder typically involving peripheral blood, spleen and bone marrow. It is commonly presenting with pancytopenia, monocytopenia and massive splenomegaly, while
Valentini Samanidou, Aikaterini Panteli, Liontos Angelos, Biros Dimitrios, Diamantina Lymperatou, Haralampos Milionis, Kapsali Eleni   +6 more
doaj   +1 more source

Acute myeloid leukemia with leukemic pleural effusion and high levels of pleural adenosine deaminase: A case report and review of literature

Open Medicine, 2021
Pleural effusions are rarely observed in association with acute myeloid leukemia (AML), and their true incidence remains unknown. Given the low diagnostic yield from cytopathologic analysis of malignant pleural effusions and the fact that patients with ...
Wang Sing-Ting, Chen Chieh-Lung, Liang Shih-Hsin, Yeh Shih-Peng, Cheng Wen-Chien   +4 more
doaj   +1 more source

EXTRAMEDULLARY BLOOD PRODUCTION [PDF]

Blood, 1949
Abstract Investigations of extramedullary foci of hematopoieses demonstrate that, in human beings, the extramedullary hematopoiesis in the fetus at term is more pronounced in the mammary glands of the female than in those of the male. The author suggests the possibility that there may be a connection between the location of the foci, and
openaire   +2 more sources

Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny, Soetojo Wirjopranoto, Chairul A. Nidom, I Ketut Sudiana, Terawan A. Putranto, Elisa D. Pratiwi, Tiza W. Mawaddah, Astria N. Nidom, Reviany V. Nidom, Setyarina Indrasari, Irma Y. Rosytania, Hiqmah Y. Yana, Sanindita Kusumastuti   +12 more
wiley   +1 more source

Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations

Frontiers in Cell and Developmental Biology, 2023
High-risk relapsed/refractory adult Philadelphia-negative (Ph−) B-cell acute lymphoblastic leukemia (B-ALL) is a great challenge due to limited possibilities to achieve and maintain a complete response. This also applies to cases with extramedullary (EM)
Anna Ferrari, Delia Cangini, Andrea Ghelli Luserna di Rorà, Andrea Ghelli Luserna di Rorà, Annalisa Condorelli, Marta Pugliese, Giovanni Schininà, Sebastiano Cosentino, Eugenio Fonzi, Chiara Domizio, Giorgia Simonetti, Salvatore Leotta, Giuseppe Milone, Giovanni Martinelli   +13 more
doaj   +1 more source

Extramedullary plasmacytoma of the eyelid [PDF]

British Journal of Ophthalmology, 2003
A 74 year old man presented with a foreign body sensation in the right eye superimposed on a slowly growing enlarging lump in the right eyelid. He had no history of recurrent infections, bleeding, weight loss, or night sweats. His only other symptom was chronic backache secondary to osteoarthritis. Past medical history included cataract extraction from
E, Ahamed, L M, Samuel, J E, Tighe
openaire   +2 more sources