Results 31 to 40 of about 37,516 (275)

Solitary extramedullary plasmacytoma of the left main bronchus: A case report and literature review

open access: yesThoracic Cancer, 2023
Tracheal tumors are rare, accounting for 0.1% of all malignancies. Squamous cell carcinoma and adenoid cystic carcinoma are the two most prevalent tracheal cancers.
Limin Gao   +5 more
doaj   +1 more source

Salvage With Revumenib: Targeting KMT2A‐Rearranged Isolated Leukemia Cutis Identified in the Extramedullary Disease [PDF]

open access: yesEJHaem
ABSTRACT Acute myeloid leukemia (AML) is an aggressive hematologic malignancy associated with a high risk of relapse. Leukemia cutis is characterized by the presence of neoplastic leukocytes infiltrating the skin. Here, we present a previously treated AML patient who relapsed with isolated leukemia cutis without bone marrow involvement. Fluorescence in
Antonios B   +9 more
europepmc   +2 more sources

A walk to remember

open access: yesJournal of Spinal Surgery, 2017
We present a rare case of thoracic congenital dermal sinus associated with an extramedullary dermoid cyst in an 18-monthold female child, who presented with a 3-month history of motor weakness of both the lower extremities.
S Vishwanath, S Pavan, H Jayanth
doaj   +1 more source

Surgical outcome of intradural extramedullary tumors: Single institutional experience—assessment using frankel grading

open access: yesJournal of Spinal Surgery, 2015
Background: To report the surgical outcome of intradural extramedullary (IDEM) tumors in 52 patients. Clinical effect was evaluated based on Frankel grade.
Vivek Kumar Kankane   +2 more
doaj   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng   +5 more
wiley   +1 more source

Synergistic Remodeling of Tumor Immune Microenvironment via a DNA Nanodevice Integrating STING Activation and Lysosome‐Targeted PD‐L1 Degradation

open access: yesAdvanced Science, EarlyView.
A rational design DNA nanoplatform not only achieves efficient PD‐L1 degradation but also triggers robust STING signaling. The nanodevice effectively reprograms “cold” tumors, leading to potent inhibition of tumor growth and metastasis in vivo. ABSTRACT The cGAS‐STING pathway is a cornerstone of innate antitumor immunity; however, its therapeutic ...
Haoxiang Li   +5 more
wiley   +1 more source

Extramedullary Hematopoiesis in Cerebellar Hemangioblastoma

open access: yes, 1991
Extramedullary hematopoiesis and paraneoplastic erythrocytosis are uncommon in cerebellar hemangioblastoma, and their concomitant occurrence has not been reported.
Natasa Zec, Javad Towfighi, Peter Cera
core   +1 more source

Diagnostic imaging of intrathoracic extramedullary haematopoiesis

open access: yes, 2023
Key message Although intrathoracic extramedullary haematopoiesis (EMH) is rare, its nodular lesions should be differentiated from malignancy. 111In‐bone marrow scintigraphy can be useful for the non‐invasive diagnosis of intrathoracic EMH because ...
Yuki Yato   +6 more
core   +1 more source

Daratumumab efficacy in extramedullary orbital myeloma [PDF]

open access: yes, 2020
Daratumumab is very efficacious in multiple myeloma. Few reports are present about efficacy in extramedullary myeloma. We report here daratumumab efficacy in extramedullary ocular myeloma in a young 46‐year‐old man diagnosed 3 years earlier and relapse ...
Bocchia, Monica   +5 more
core   +1 more source

Conjunctival mass as the initial presentation of acute lymphoblastic leukemia in a child

open access: yesIndian Journal of Medical and Paediatric Oncology, 2019
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy with excellent survival. ALL has varied presentations. Presentation of ALL as a conjunctival mass is very rare.
Jagdish Prasad Meena   +6 more
doaj   +1 more source

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