Results 41 to 50 of about 6,047 (304)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Пересечение множества экстремальных функций для двух функционалов [PDF]

open access: yesПроблемы анализа, 2010
В работе исследована экстремальная задача для линейного функционала в классе U'α. В частности, получен вид экстремальной функции.Research extremal problem for linear functional in U'α is studied. In particular, a form of extremal function is got.
Ефремова И. С.
doaj  

Einstein-Maxwell-scalar black holes: classes of solutions, dyons and extremality

open access: yesJournal of High Energy Physics, 2019
Spherical black hole (BH) solutions in Einstein-Maxwell-scalar (EMS) models wherein the scalar field is non-minimally coupled to the Maxwell invariant by some coupling function are discussed. We suggest a classification for these models into two classes,
D. Astefanesei   +3 more
doaj   +1 more source

The statistical mechanics of near-extremal black holes

open access: yesJournal of High Energy Physics, 2021
An important open question in black hole thermodynamics is about the existence of a “mass gap” between an extremal black hole and the lightest near-extremal state within a sector of fixed charge.
Luca V. Iliesiu, Gustavo J. Turiaci
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Positive extremal values and solutions of the exponential equations with application to automatics [PDF]

open access: yesBulletin of the Polish Academy of Sciences: Technical Sciences, 2020
In the paper, maximal values xe(τ) of the solutions x(t) of the linear differential equations excited by the Dirac delta function are determined. There are obtained the analytical solutions of the equations and also the maximal positive values of these ...
H. Górecki, M. Zaczyk
doaj   +1 more source

On the homogeneous extremal function for the standard simplex

open access: yes, 2018
In this paper an explicit formula for the homogeneous Siciak’s extremal function is computed in the case of standard simplex in RN. There are discussed some problems related to this result.
Baran, M.
core   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

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