Results 51 to 60 of about 5,422,793 (299)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Extremal functions for real convex bodies: simplices, strips, and ellipses [PDF]
, 2021 We present an explicit method to compute the (Siciak-Zaharjuta) extremal function of a real convex polytope in terms of supporting simplices and strips.
Ma`u, Sione, Sione Ma‘u
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Sufficient optimality conditions based on functional increment formulas in control problems
Известия Иркутского государственного университета: Серия "Математика", 2014 A typical optimal control problem with convex terminal function is considered. Sufficient optimality conditions are obtained with the help non-standard functional increment formulas.
V.A. Srochko +2 more
doaj
The Extremal Function For Noncomplete Minors [PDF]
Combinatorica, 2005 We investigate the maximum number of edges that a graph G can have if it does not contain a given graph H as a minor (subcontraction). Let $$c{\left( H \right)} = \inf {\left\{ {c:e{\left( G \right)} \geqslant c{\left| G \right|}{\text{implies}}{\kern 1pt} {\kern 1pt} G \succ H} \right\}}.$$We define a parameter γ(H) of the graph H and show that, if H ...
Joseph Samuel Myers +1 more
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The extremal function for Petersen minors [PDF]
Journal of Combinatorial Theory, Series B, 2018 We prove that every graph with $n$ vertices and at least $5n-8$ edges contains the Petersen graph as a minor, and this bound is best possible. Moreover we characterise all Petersen-minor-free graphs with at least $5n-11$ edges. It follows that every graph containing no Petersen minor is 9-colourable and has vertex arboricity at most 5.
Kevin Hendrey, David R. Wood
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
BERGMANN AND HARDY SPACES AND CONJUGATE OF THEM
Вестник Донского государственного технического университета, 2018 It is proved that space is strongly notmed, and is neither strongly notmed, nor uniformly convex. A standard form of the linear functionals over space and over metric spaces of 0 < p £ 1, is determined.
Galina Y. Ryabykh, Vladimir G. Ryabykh
doaj
Sharp affine weighted L 2 Sobolev inequalities on the upper half space
Advanced Nonlinear StudiesWe establish some sharp affine weighted L 2 Sobolev inequalities on the upper half space, which involves a divergent operator with degeneracy on the boundary.
Dou Jingbo, Hu Yunyun, Yue Caihui
doaj +1 more source