Results 51 to 60 of about 2,351 (264)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
In this paper, we study an extremal problem involving best approximation in the Hardy space $H^1$ on the unit disk $\mathbb D$. Specifically, we consider weighted combinations of the Cauchy-Szegö kernel and its derivative, parameterized by an inner ...
V.V. Savchuk, M.V. Savchuk
doaj +1 more source
Time Eigenstates for Potential Functions without Extremal Points
In a previous paper, we introduced a way to generate a time coordinate system for classical and quantum systems when the potential function has extremal points.
Gabino Torres-Vega
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Engineering zero modes in transformable mechanical metamaterials
Reconfigurable elastic properties are essential for functional mechanical metamaterials. Here, the authors propose a 3D metamaterial with engineered zero modes, and experimentally demonstrate its transformability covering all seven extremal metamaterial ...
Zhou Hu +6 more
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Extremal functions for Bloch constants [PDF]
The author establishes an intriguing inequality for a function f that is holomorphic in the open unit disk \({\mathbb{D}}\) and extremal for any one of the following: the Bloch, Landau, locally schlicht Bloch or univalent Bloch constant. If f is such an extremal function, then \[ | \lim_{\epsilon \to 0}\frac{1}{\pi}\int_{\epsilon
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A note on solutions of Schiffer's differential equation
We consider Schiffer's differential equation for functions in the class of normalized univalent functions which maximize the nth¯ coefficient. By considering a class of functionals converging to the nth¯ coefficient functional, we determine some ...
Ronald J. Leach
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The extremal function for Petersen minors [PDF]
We prove that every graph with $n$ vertices and at least $5n-8$ edges contains the Petersen graph as a minor, and this bound is best possible. Moreover we characterise all Petersen-minor-free graphs with at least $5n-11$ edges. It follows that every graph containing no Petersen minor is 9-colourable and has vertex arboricity at most 5.
Kevin Hendrey, David R. Wood
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

