Results 71 to 80 of about 2,351 (264)

Oszacowanie parametrów liniowych okrętu w pewnym zbiorze obciążeń

Engineering Transactions, 1966
Estimation of the linear parameters of a ship in some a set loads The object of the considerations is the problem of integral extrema of the functional (2.1) in the set (2.3) of continuous functions having sectionally continuous derivatives.
Jan WIĘCKOWSKI
doaj  

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Extremality of Koebe’s Function

Axioms
The remarkable Koebe function is the (unique) extremal of many important distortion functionals in geometric function theory. This paper provides a complete characterization of such functionals.
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Extremal functions and best approximate formulas for the Hankel-type Fock space

Cubo
In this paper we recall some properties for the Hankel-type Fock space \(\mathscr{F}_{\alpha,\ast}(\mathbb{C}^d)\). This space was introduced by Cholewinsky in 1984 and plays a background to our contribution. Especially, we examine the extremal functions
Fethi Soltani
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

A note on extremal functions for sharp Sobolev inequalities

Electronic Journal of Differential Equations, 2007
In this note we prove that any compact Riemannian manifold of dimension $ngeq 4$ which is non-conformal to the standard n-sphere and has positive Yamabe invariant admits infinitely many conformal metrics with nonconstant positive scalar curvature on
Marcos Montenegro, Ezequiel R. Barbosa
doaj  

The extremal function for disconnected minors

Journal of Combinatorial Theory, Series B, 2017
For a graph $H$ let $c(H)$ denote the supremum of $|E(G)|/|V(G)|$ taken over all non-null graphs $G$ not containing $H$ as a minor. We show that $$c(H) \leq \frac{|V(H)|+\mathrm{comp}(H)}{2}-1,$$ when $H$ is a union of cycles, verifying conjectures of Reed and Wood, and Harvey and Wood.
Endre Csóka, Irene Lo, Sergey Norin, Hehui Wu, Liana Yepremyan   +4 more
openaire   +4 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source