Results 41 to 50 of about 1,376 (263)

Zeroth-order general Randić index of cactus graphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2019
A connected graph G is said to be cactus if no two cycles of G have any common edge. The present note is devoted to developing some extremal results for the zeroth-order general Randić index of cactus graphs and finding some sharp bounds on this index ...
Hassan Ahmed   +2 more
doaj   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Exact solutions to the Erdős-Rothschild problem

open access: yesForum of Mathematics, Sigma
Let $\boldsymbol {k} := (k_1,\ldots ,k_s)$ be a sequence of natural numbers. For a graph G, let $F(G;\boldsymbol {k})$ denote the number of colourings of the edges of G with colours $1,\dots ,s$ such that, for every $c \in \{1 ...
Oleg Pikhurko, Katherine Staden
doaj   +1 more source

Unicyclic Graphs with the Fourth Extremal Wiener Indices

open access: yesJournal of Chemistry, 2020
A graph is called unicyclic if the graph contains exactly one cycle. Unicyclic graphs with the fourth extremal Wiener indices are characterized. It is shown that, among all unicyclic graphs with n≥8 vertices, C5Sn−4 and C2u1,u2S3,Sn−4 attain the fourth ...
Guangfu Wang   +3 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Some new upper bounds of

open access: yesAKCE International Journal of Graphs and Combinatorics, 2017
The extremal number or simply denotes the maximal number of edges in a graph on vertices with forbidden subgraphs and . The exact number of is only known for up to and . There are upper and lower bounds of for other values of .
Novi H. Bong
doaj   +1 more source

On Hamiltonian Cycles in Claw-Free Cubic Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2022
We show that every claw-free cubic graph of order n at least 8 has at most 2⌊n4⌋{2^{\left\lfloor {{n \over 4}} \right\rfloor }} Hamiltonian cycles, and we also characterize all extremal graphs.
Mohr Elena, Rautenbach Dieter
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Commuting graphs and extremal centralizers

open access: yesArs Mathematica Contemporanea, 2013
We determine the conditions for matrix centralizers which can guarantee the connectedness of the commuting graph for the full matrix algebra M n ( F ) over an arbitrary field F . It is known that if F is an algebraically closed field and n  ≥ 3 , then the diameter of the commuting graph of M n ( F ) is always equal to four.
Dolinar, Gregor   +3 more
openaire   +4 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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