Results 51 to 60 of about 1,376 (263)
Spectral extremal graphs for the bowtie
Discrete Mathematics, 2023 22 pages, 6 figures.
Yongtao Li, Lu Lu, Yuejian Peng
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Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Extremal Graphs for Intersecting Triangles
Journal of Combinatorial Theory, Series B, 1995 A \(k\)-fan is a graph with \(2k+ 1\) vertices consisting of \(k\) 3-cycles having one vertex in common. The authors show that if \(n\geq 50k^2\) and the graph \(G_n\) has more than \([n^2/4]+ k^2- ck\) edges, where \(c\) equals 1 or 3/2 according as \(k\) is odd or even, then \(G_n\) contains a \(k\)-fan; furthermore, the bound for the number of edges
Paul Erdös +3 more
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MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
The hyper-Zagreb index of cacti with perfect matchings
AKCE International Journal of Graphs and Combinatorics, 2020 Let be a simple connected graph. The hyper-Zagreb index is defined as . A connected graph is a cacti if all blocks of are either edges or cycles. Let be the set of cacti of order with a perfect matching and cycles. In this paper, we determine sharp upper
Hechao Liu, Zikai Tang
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
MathematicsDegree-based topological indices play a central role in characterizing graph structures and their chemical applications. Among these, multiplicative Zagreb indices have attracted considerable attention due to their strong discriminative power and ...
Mahdieh Azari +2 more
doaj +1 more source
Spectral extremal graphs for fan graphs
Discrete Mathematics21 pages,2 ...
Loujun Yu, Yongtao Li, Yuejian Peng
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source