Results 141 to 150 of about 34,637 (273)
Advanced Science, EarlyView.The authors complement bovine pan‐SV with massive novel structural variations (SVs) identified through long‐read sequencing of 83 globally distributed cattle breeds. Repetitive sequence‐mediated SVs (rep‐SV) exhibit distinct dynamic patterns throughout cattle sub‐speciation and/or domestication processes, including uneven distribution between chr‐X and
Zhifan Guo +16 more
wiley +1 more source
The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models
Advanced Science, EarlyView.Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková +5 more
wiley +1 more source
Engineering an Optogenetic pH‐Modulator in Bacteria
Advanced Science, EarlyView.ABSTRACT Cells in many naturally occurring organisms routinely cooperate to control their extracellular pH in a dynamic and reversible manner, but this capability has been underexplored in synthetic biology. Here, we sought to engineer a microbial system that switches between two states —high and low extracellular pH— with minimal human intervention ...
Jenevieve Kuang +7 more
wiley +1 more source
Problems in extremal graphs and poset theory
, 2018 In this dissertation, we present three different research topics and results regarding such topics. We introduce partially ordered sets (posets) and study two types of problems concerning them-- forbidden subposet problems and induced-poset-saturation problems. We conclude by presenting results obtained from studying vertex-identifying codes in graphs.
openaire +3 more sources
MGDP: Mastering a Generalized Depth Perception Model for Quadruped Locomotion
Advanced Science, EarlyView.ABSTRACT Perception‐based Deep Reinforcement Learning (DRL) controllers demonstrate impressive performance on challenging terrains. However, existing controllers still face core limitations, struggling to achieve both terrain generality and platform transferability, and are constrained by high computational overhead and sensitivity to sensor noise.
Yinzhao Dong +9 more
wiley +1 more source
Artificial Intelligence Powers Protein Functional Annotation
Advanced Science, EarlyView.This review systematically summarizes how artificial intelligence advances protein functional annotation. It organizes existing methods into six unified modeling paradigms and analyzes their applications in Gene Ontology and Enzyme Commission prediction.
Wenkang Wang +4 more
wiley +1 more source
On the minimal length of the longest trail in a fixed edge-density graph
Open Mathematics, 2013 Szécsi Vajk
doaj +1 more source
PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping
Advanced Science, EarlyView.scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su +7 more
wiley +1 more source
From graph theory to chemoinformatics: modified bond-based indices and a hypothesis-driven multi-task QSAR/QSPR benchmark. [PDF]
Sci RepAltairi A +3 more
europepmc +1 more source
Bioinspired Morphology‐Decoupled Soft Gripper with Enhanced Bidirectional Grasping Capability
Advanced Science, EarlyView.Inspired by biological predation, a novel gripper decouples cross‐modal grasping via dual morphological configurations. Synergistically integrating hybrid rigid and soft coupled fingers with a metamaterial palm, the system performs active compliant grasping for static objects and passive cage capture for dynamic targets.
Yedong Huang +4 more
wiley +1 more source