Results 61 to 70 of about 371,529 (264)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Scaling in the timing of extreme events [PDF]

Chaos, Solitons & Fractals, 2015
Extreme events can come either from point processes, when the size or energy of the events is above a certain threshold, or from time series, when the intensity of a signal surpasses a threshold value. We are particularly concerned by the time between these extreme events, called respectively waiting time and quiet time.
openaire   +3 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Public Support for Disaster Risk Reduction: Evidence from The Bahamas Before and After Hurricane Dorian

Social Sciences
Studies in public policy have suggested that disasters can potentially serve as “focusing events”, catalyzing significant changes to disaster risk reduction (DRR) policies and practices. How and why this effect does (or does not) ensue, and for how long,
Barry S. Levitt, Richard S. Olson
doaj   +1 more source

PULSAR OBSERVATIONS OF EXTREME SCATTERING EVENTS [PDF]

The Astrophysical Journal, 2015
Extreme scattering events (ESEs) in the interstellar medium (ISM) were first observed in regular flux measurements of compact extragalactic sources. They are characterized by a flux variation over a period of weeks, suggesting the passage of a 'diverging plasma lens' across the line of sight (LOS).
W. A. Coles, M. Kerr, R. M. Shannon, G. B. Hobbs, R. N. Manchester, X.-P. You, M. Bailes, N. D. R. Bhat, S. Burke-Spolaor, S. Dai, M. J. Keith, Y. Levin, S. Osłowski, V. Ravi, D. Reardon, L. Toomey, W. van Straten, J. B. Wang, L. Wen, X. J. Zhu   +19 more
openaire   +7 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Extreme weather events inWest Hungary

International Journal of Horticultural Science, 2010
Agricultural production is a rather risky activity, as it is largely exposed to extreme weather events. This paper focuses on the frost and hail data in springtime, affecting fruit production in West Hungary.
Z. Mézes, M. Gaál, K. Szentteleki, M. Soltész, J. Nyéki, Z. Szabó   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Modelling Extreme Multivariate Events

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1991
SUMMARY The classical treatment of multivariate extreme values is through componentwise ordering, though in practice most interest is in actual extreme events. Here the point process of observations which are extreme in at least one component is considered.
Coles, Stuart G., Tawn, Jonathan A.
openaire   +2 more sources