Results 51 to 60 of about 409,631 (265)

The norming set of a bilinear form on a certain normed space $\mathbb{R}^2$

open access: yesResearches in Mathematics
In this paper we classify the norming set of a bilinear form on the plane with a certain norm whose unit ball has only four extreme points. We obtain the results of [6, 8] as corollary.
S.G. Kim
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Certain classes of harmonic functions pertaining to special functions [PDF]

open access: yesМатематичні Студії, 2011
Making use of generalized Dziok-Srivastava operator we introduced a new class of complexvalued harmonic functions which are orientation preserving, univalent and starlike in the unit disc.
G. Murugusundaramoorthy   +2 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

On the extreme points of some classes of holomorphic functions

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1997
Let U be the unit disk, D⊃U an open connected set and z0∈D. Let also P(z0,c,D) be the class of holomorphic functions in D for which f(z0)=c and Ref(z)>0 in U. We find the extreme points of the class P(z0,c,D).
Nicolas Samaris
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Extreme points and rotundity of Orlicz-Sobolev spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
It is well known that Sobolev spaces have played essential roles in solving nonlinear partial differential equations. Orlicz-Sobolev spaces are generalized from Sobolev spaces.
Shutao Chen   +2 more
doaj   +1 more source

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