Results 61 to 70 of about 2,366,719 (285)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Extreme phase and rotated quadrature measurements
, 2009 We determine the extreme points of the convex set of covariant phase observables. Such extremals describe the best phase parameter measurements of laser light - the best in the sense that they are free from classical randomness due to fluctuations in the
Carmeli C +8 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A graph/particle-based method for experiment design in nonlinear systems
, 2014 We propose an extended method for experiment design in nonlinear state space models. The proposed input design technique optimizes a scalar cost function of the information matrix, by computing the optimal stationary probability mass function (pmf) from ...
Dahlin, Johan +3 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Traces on cores of C*-algebras associated with self-similar maps
, 2012 We completely classify the extreme tracial states onthe cores of the C*-algebras associated with self-similar maps on compact metric spaces. We present a complete list of them.
Falconer +5 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Extreme and exposed symmetric bilinear forms on the space ${\mathcal L}_{s}(^2 l_{\infty}^2)$
Karpatsʹkì Matematičnì Publìkacìï, 2020 We classify extreme points and exposed points of the unit ball of the space of bilinear symmetric forms on the real Banach space of bilinear symmetric forms on $l_{\infty}^2.$ It is shown that for this case, the set of extreme points is equal to the set ...
Sung Guen Kim
doaj +1 more source
Risk analysis for green water of single-point moored ship
Zhongguo Jianchuan Yanjiu, 2021 ObjectiveThe purpose of this paper is to predict the green water risks of a single-point moored ship.MethodsTherefore, a combined method of coupled dynamic analysis and air gap analysis is proposed.
Wei YANG +5 more
doaj +1 more source