Results 61 to 70 of about 425,476 (265)
Extreme Points and Support Points of Subordination Families
The family \(A\) of analytic functions \(f\) of the unit disk \(\Delta\), equipped with the topology of uniform convergence in compact subsets forms a locally convex linear space. Let \(B_0:=\{\omega\in A |\omega(0)=0, |\omega|0\}=\{p\in A |p\prec {1+z \over 1-z}\} =s({1+z \over 1-z}) . \] The Krein-Milman theorem guarantees that a subordination family
Hallenbeck, David J, Hallenbeck, K.T
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Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
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On the extreme points of moments sets [PDF]
Necessary and sufficient conditions for a measure to be an extreme point of the set of measures (on an abstract measurable space) with prescribed generalized moments are given, as well as an application to extremal problems over such moment sets; these conditions are expressed in terms of atomic partitions of the measurable space. It is also shown that
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The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
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Extreme points and rotundity of Orlicz-Sobolev spaces
It is well known that Sobolev spaces have played essential roles in solving nonlinear partial differential equations. Orlicz-Sobolev spaces are generalized from Sobolev spaces.
Shutao Chen +2 more
doaj +1 more source
Conjugate points on a limiting extremal [PDF]
Theorem 1 , together with the author's extensions of the Sturmian Comparison Theorems, will suffice to establish the basic Theorem 27.3, p. 211 of Global Variational Analysis: Weierstrass Integrals on a Riemannian Manifold. Mathematical Notes , Princeton University Press, Princeton, N.J., 1976.
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Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
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Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
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Non-extreme-Points Approach to Extreme Points of Integral Families of Analytic Functions
Non extreme points of compact, convex integral families of analytic functions are investigated. Knowledge about extreme points provides a valuable tool in the optimization of linear extremal problems. The functions studied are determined by a 2-parameter collection of kernel functions integrated against measures on the torus.
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Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
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