Results 81 to 90 of about 409,631 (265)
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Fast Extended One-Versus-Rest Multi-Label Support Vector Machine Using Approximate Extreme Points
IEEE Access, 2017 Existing extended one-versus-rest multi-label support vector machine (OVR-ESVM) adopting non-linear kernel is seriously restricted by excessive training time when it is applied to large-scale data set.
Zhongwei Sun +5 more
doaj +1 more source
On the extreme points and strongly extreme points in Köther-Bochner spaces
Publications de l'Institut Mathematique, 2012 We give the necessary conditions of extreme points and strongly extreme points in the unit ball of K?the-Bochner spaces. The conditions have been shown to be sufficient earlier.
Hou, Zhentao, Pan, Jinghong
openaire +2 more sources
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Asymptotic farthest points and extreme points
Filomat, 2018 Let X be a normed space, G a nonempty bounded subset of X and fxng a bounded sequence in X. In this article, we introduce and discuss the concept of asymptotic farthest points of fxng in G, which is a new definition in abstract approximation theory.
Ardakani, M. Zare Nejhad +1 more
openaire +3 more sources
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Certain subclasses of analytic functions with varying arguments
Le Matematiche, 2014 In this paper, we introduce new classes VM(β ) and VN(β ) of analytic functions with varying arguments in the open unit disc U = {z ∈ C : |z| <1}. Some properties such as coefficient estimates, extreme points, distortion theorems for functions f (z ...
Mohamed K. Aouf +2 more
doaj
Extreme points and convolution properties of some classes of multivalent functions
International Journal of Mathematics and Mathematical Sciences, 1996 This paper deals with the extreme points of closed convex hulls of the classes of multivalent functions related to Ruscheweyh derivatives and then these are used to determine the coefficient bounds.
O. P. Ahuja
doaj +1 more source
Impact of Positive Lifestyle Behaviors on Direct Health Care Cost Savings for Low Back Pain
Arthritis Care &Research, EarlyView.Objective This study aimed to investigate the relationship between a previously purpose‐developed lifestyle behavior scale and health care cost savings related to low back pain (LBP). Methods This longitudinal study used data from the Australian Twin Back (AUTBACK) study. LBP and lifestyle behavior measures were collected at baseline. Physical activity
Ye Tian +8 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai +12 more
wiley +1 more source