Results 61 to 70 of about 9,847,764 (300)

Single-index models for extreme value index regression

open access: yes, 2022
Abstract Since the extreme value index (EVI) controls the tail behaviour of the distribution function, the estimation of EVI is a very important topic in extreme value theory. Recent developments in the estimation of EVI along with covariates have been in the context of nonparametric regression.
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Ultimate 100m World Records Through Extreme-Value Theory [PDF]

open access: yes
We use extreme-value theory to estimate the ultimate world records for the 100m running, for both men and women. For this aim we collected the fastest personal best times set between January 1991 and June 2008.
Einmahl, J.H.J., Smeets, S.G.W.R.
core   +2 more sources

Estimating the Occurrence of Geomagnetic Activity Using the Hilbert‐Huang Transform and Extreme Value Theory

open access: yesSpace Weather, 2020
In this paper extreme value theory (EVT) has been used to estimate the return levels for geomagnetic activity based on the aa index. The aa index is the longest, continuously recorded, geomagnetic data set (from 1868 to present). This long, 150‐year data
Sean Elvidge
doaj   +1 more source

Improving the bias of a pseudo-maximum likelihood estimate of the extreme value index by k-records

open access: yesJournal of Statistical Theory and Applications (JSTA), 2023
The paper focusses on the estimation of the extreme value index in terms of k-records based on a maximum likelihood approach, which is suggested recently by Louzaoui and El Arrouchi (J Probab Stat, 2020).
Abderrahim Louzaoui, Mohamed El Arrouchi
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Extreme value theory applied to the standardized precipitation index - doi: 10.4025/actascitechnol.v36i1.17475

open access: yesActa Scientiarum: Technology, 2014
The Standardized Precipitation Index (SPI) is a mathematical algorithm developed for detecting and characterizing precipitation departures with regard to an expected regional climate condition.
Gabriel Constantino Blain
doaj   +1 more source

Extreme value theory in emerging markets [PDF]

open access: yesEkonomski Anali, 2010
This paper investigates the performance of extreme value theory (EVT) with the daily stock index returns of four different emerging markets. The research covers the sample representing the Serbian (BELEXline), Croatian (CROBEX), Slovenian (SBI20), and ...
Anđelić Goran   +2 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Nonparametric smoothing in extreme value theory [PDF]

open access: yes, 2010
Includes bibliographical references (leaves 137-138).This work investigates the modelling of non-stationary sample extremes using a roughness penalty approach, in which smoothed natural cubic splines are fitted to the location and scale parameters of the
Clur, John-Craig
core   +1 more source

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