Results 71 to 80 of about 9,847,764 (300)
Accounting for choice of measurement scale in extreme value modeling [PDF]
, 2010 We investigate the effect that the choice of measurement scale has upon inference and extrapolation in extreme value analysis. Separate analyses of variables from a single process on scales which are linked by a nonlinear transformation may lead to ...
Jonathan, Philip +2 more
core +5 more sources
A New Class of Reduced-Bias Generalized Hill Estimators
MathematicsThe estimation of the extreme value index (EVI) is a crucial task in the field of statistics of extremes, as it provides valuable insights into the tail behavior of a distribution.
Lígia Henriques-Rodrigues +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Extreme Value Index Estimators and Smoothing Alternatives: A Critical Review [PDF]
Extreme-value theory and corresponding analysis is an issue extensively applied in many different fields. The central point of this theory is the estimation of a parameter γ, known as the extreme-value index. In this paper we review several extreme-value
Panaretos, John, Tsourti, Zoi
core
Correction of the paper “Bicyclic graphs with extremal values of PI index”
Discrete Applied Mathematics, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gang Ma 0005, Qiuju Bian
openaire +3 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Extreme Value Index Estimators and Smoothing Alternatives: Review and Simulation Comparison [PDF]
Extreme-value theory and corresponding analysis is an issue extensively applied in many different fields. The central point of this theory is the estimation of a parameter γ, known as extreme-value index.
Panaretos, John, Tsourti, Zoi
core
Scientific ReportsChannel-forming discharge (D cf) is an important parameter in river management and reservoir flood regulation. Applying the methods for calculating D cf to reaches downstream reservoirs characterized by drastic changes in water and sediment conditions ...
Hua Ge, Lingling Zhu
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source