Results 11 to 20 of about 111,108 (251)
High-throughput binding affinity calculations at extreme scales [PDF]
BMC Bioinformatics, 2018 Resistance to chemotherapy and molecularly targeted therapies is a major factor in limiting the effectiveness of cancer treatment. In many cases, resistance can be linked to genetic changes in target proteins, either pre-existing or evolutionarily selected during treatment.
Jumana Dakka +7 more
openaire +6 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation. [PDF]
FEBS Open BioAn iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Tomkova M, Mirossay A, Sedlak E.
europepmc +2 more sources
Applications of CRISPR screening to lung cancer treatment
Frontiers in Cell and Developmental Biology, 2023 Lung cancer is an extremely aggressive and highly prevalent disease worldwide, and it is one of the leading causes of cancer death. Deciphering intrinsic genetic mechanism, finding new targets, and overcoming drug resistance are the key to lung cancer ...
Wanying Shen +6 more
doaj +1 more source
Applied Sciences, 2020 The representative media access control (MAC) mechanism of IEEE 802.11 is a distributed coordination function (DCF), which operates based on carrier-sense multiple access with collision avoidance (CSMA/CA) with binary exponential backoff.
Taewon Song, Taeyoon Kim
doaj +1 more source
BioChem, 2021 In the race against COVID-19 for timely therapeutic developments, mass spectrometry-based high-throughput methods have been valuable. COVID-19 manifests an extremely diverse spectrum of phenotypes from asymptomatic to life-threatening, drastic elevations
Diane Appiasie +5 more
doaj +1 more source
Current Status and Directions of IEEE 802.11be, the Future Wi-Fi 7
IEEE Access, 2020 While customers rivet their eyes on Wi-Fi 6, in the bowels of the IEEE 802.11 Working Group that creates Wi-Fi standards, the next generation Wi-Fi is being developed.
Evgeny Khorov +2 more
doaj +1 more source
Hypothesis testing at the extremes: fast and robust association for high-throughput data [PDF]
Biostatistics, 2015 A number of biomedical problems require performing many hypothesis tests, with an attendant need to apply stringent thresholds. Often the data take the form of a series of predictor vectors, each of which must be compared with a single response vector, perhaps with nuisance covariates.
Zhou, Yi-Hui, Wright, Fred
openaire +3 more sources
High-Speed Privacy Amplification Scheme Using GMP in Quantum Key Distribution
IEEE Photonics Journal, 2020 Privacy amplification (PA) is the art of distilling a highly secret key from a partially secure string by public discussion. It is a vital procedure in quantum key distribution (QKD) to produce a theoretically unconditional secure key.
Bingze Yan +3 more
doaj +1 more source
BMC Genomics, 2019 Background Chromatin immunoprecipitation coupled to sequencing (ChIP-seq) is widely used to map histone modifications and transcription factor binding on a genome-wide level.
Charlotte Gustafsson +3 more
doaj +1 more source
High throughput viscoelastic particle focusing and separation in spiral microchannels
Scientific Reports, 2021 Passive particle manipulation using inertial and elasto-inertial microfluidics have received substantial interest in recent years and have found various applications in high throughput particle sorting and separation.
Tharagan Kumar +5 more
doaj +1 more source