Results 51 to 60 of about 1,039,132 (290)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
On extremum properties of orthogonal quotients matrices [PDF]
, 2010 In this paper we explore the extremum properties of orthogonal quotients matrices. The orthogonal quotients equality that we prove expresses the Frobenius norm of a difference between two matrices as a difference between the norms of two matrices.
Dax, Achiya
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An extremum principle for the analysis and design of constitutively nonlinear systems.
, 1994 The actual nonlinear constitutive character of most elastic materials is often approximated in engineering analysis by a linear relation-generalized Hooke's law. This approximation may introduce significant error into an analysis problem.
Plaxton, Sheldon Kent
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Improved Particle Swarm Optimization Geomagnetic Matching Algorithm Based on Simulated Annealing
IEEE Access, 2020 As a new assistant navigation technology using geophysical field for navigation, geomagnetic matching navigation can effectively alleviate the problems such as the unavailability of satellite and the easy divergence of position data of inertial ...
Caijuan Ji, Qingwei Chen, Chengying Song
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Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
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Illustration of the extremum principle.
, 2019 The extremum principle states that the dimensionality of the solution space is determined by the number of enzyme-expression constraints, rather than by the dimensionality of the metabolic network.
Frank J. Bruggeman (193875) +4 more
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On the connection between optimality conditions, variational inequalities and equilibrium problems
Le Matematiche, 1994 In this note we underline, once more, the relationships between necessary optimality conditions for constrained extremum problems and the variational inequalities in finite dimension spaces.
Massimo Pappalardo
doaj
PLoS Computational Biology, 2019 Growth rate is a near-universal selective pressure across microbial species. High growth rates require hundreds of metabolic enzymes, each with different nonlinear kinetics, to be precisely tuned within the bounds set by physicochemical constraints. Yet,
Daan H de Groot +4 more
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The absolute stabilization and optimal control of hydrofoil watercrafts [PDF]
INCAS Bulletin, 2018 Hydrofoil watercrafts have a technology through which immersed wings are mounted under the hull. In the longitudinal movement case, these transversal wings are developing a carrying capacity which lifts the ship, thus decreasing the wet surface.
Mircea LUPU +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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