Results 61 to 70 of about 1,039,132 (290)

From the Extremum Principle of Entransy Dissipation to Steady Balance Equations of Fluid Mechanics

open access: yes, 2010
In the present work, an extremum principle of entransy dissipation is developed by taking into account the contribution of fluid friction. It is found that this extremum principle of entransy dissipation leads to the same balance equations as given in ...
Mingtian Xu, Lin Cheng
core   +1 more source

Distribution Function of the Atoms of Spacetime and the Nature of Gravity

open access: yesEntropy, 2015
The fact that the equations of motion for matter remain invariant when a constant is added to the Lagrangian suggests postulating that the field equations of gravity should also respect this symmetry. This principle implies that: (1) the metric cannot be
Thanu Padmanabhan
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Using the quantum probability ranking principle to rank interdependent documents [PDF]

open access: yes, 2010
A known limitation of the Probability Ranking Principle (PRP) is that it does not cater for dependence between documents. Recently, the Quantum Probability Ranking Principle (QPRP) has been proposed, which implicitly captures dependencies between ...
Azzopardi, L.   +5 more
core   +3 more sources

Analysis of geometrically non-linear elastic-plastic framed structures/Tampriai plastinų geometriškai netiesinių strypinių konstrukcijų analizė

open access: yesJournal of Civil Engineering and Management, 1998
A stress-strain field (SSF) evaluation of elastic-plastic structures under the action of a completely specified external loading that doesn't exceed its limiting value, but produces plastic deformation, is under consideration.
Romualdas Karkauskas
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

On the Epistemology of the Precautionary Principle [PDF]

open access: yes, 2014
In this paper we present two distinctly epistemological puzzles that arise forone who aspires to defend the precautionary principle. The first puzzle involves anapplication of contextualism in epistemology; and the second puzzle concerns the task of ...
Carter, J.A.   +5 more
core   +2 more sources

Analytical, numerical, and biomedical aspects of boundary value problems for third-order elliptic-type equations with singular coefficients

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
Mathematical modeling of various real-world processes frequently leads to boundary value problems (BVPs) for third-order partial differential equations of mixed and composite types, which have no classical analogues in mathematical physics. Foundational
N.K. Ochilova, D.B. Eshmamatova
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Extremum principle for the Hadamard derivatives and its application to nonlinear fractional partial differential equations

open access: yes, 2019
In this paper we obtain new estimates of the Hadamard fractional derivatives of a function at its extreme points. The extremum principle is then applied to show that the initial-boundary-value problem for linear and nonlinear time-fractional diffusion ...
Kirane, Mokhtar, Torebek, Berikbol
core   +1 more source

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