Results 31 to 40 of about 472,611 (268)

Cases of Undiagnosed Open Eye Injury: Clinical Features, Diagnosis and Surgical Treatment

open access: yesOftalʹmologiâ, 2019
Open eye injury (OTG), in the structure of eye damage is up to 35.0–85.0 %, the level of disability among the working part of the male population from 26 to 55 years ranges from 25.0–47.5 %, and the removal of the eyeball due to traumatic pathology is 6 ...
E. V. Chentsova   +6 more
doaj   +1 more source

Eye diseases in travelers

open access: yesInternational Maritime Health, 2020
Travelling has been growing in popularity over the last several decades. Eye diseases, e.g. decreased visual acuity, inflammatory or degenerative lesions, chronic diseases or eye trauma, affect all groups of travelers. The main risk factors contributing to the manifestation or exacerbation of common ocular diseases include exposure to dry air (inside ...
openaire   +3 more sources

Impact of fractal visual stimulation on healthy rabbit retina: functional, morphometric and biochemical studies

open access: yesРоссийский офтальмологический журнал, 2022
Purpose: to investigate the changes of electrophysiological activity of healthy rabbit retina occurring in courses of fractal stimulation (FS) of varied duration in order to obtain new scientific data on how fractal visual signals of low intensity, self ...
V. V. Neroev   +8 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Features of the Composition of Cytokines of Various Biological Effects in Patients with Uveal Melanoma: Analysis of Blood Serum. Part 2

open access: yesOftalʹmologiâ, 2022
Purpose. Conduct extended analysis of cytokine status and its role in inflammatory processes in uveal melanoma based on multiplex analysis of blood serum.Patients and methods.
V. V. Neroev   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

DIFFUSION TENSOR TRACTOGRAPHY IN THE DIAGNOSIS OF CHANGES IN THE CENTRAL DEPARTMENTS OF THE VISUAL ANALYZER IN PRIMARY GLAUCOMA

open access: yesOftalʹmologiâ, 2017
Purpose. To investigate the potential of diffusion tensor MRT (DT-MRT) in diagnosing the changes of central departments of the visual analyzer in primary open angle glaucoma.Patients and Methods.
V. P. Erichev   +3 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Multifunctional Protein Alpha2-Macroglobulin in Tear Fluid and Blood Serum of Patients with Glaucoma

open access: yesOftalʹmologiâ, 2023
Alpha2-macroglobulin (α2-MG) is a multifunctional glycoprotein. Due to the variety of its functions there can be several ways of its involvement in the pathogenesis of the glaucomatous optic neuropathy, including neuroinflammation, amyloid deposition ...
N. B. Chesnokova   +7 more
doaj   +1 more source

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