Results 51 to 60 of about 761,667 (331)

The Secrets of Salient Object Segmentation [PDF]

, 2014
In this paper we provide an extensive evaluation of fixation prediction and salient object segmentation algorithms as well as statistics of major datasets.
Hou, Xiaodi, Koch, Christof, Li, Yin, Rehg, James M., Rehg, James M., Yuille, Alan L.   +5 more
core   +6 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A mechanical device for precise self-administration of ocular drugs

Human Factors in Healthcare
Individuals with glaucoma are routinely prescribed and required to self-administer eye drop-based medication multiple times a day. Unfortunately, the process of self-administering eye drops requires a level of dexterity, strength, and visual acuity that ...
Jesse George-Akpenyi, Benjamin Lahner, Seung Hyeon Shim, Carly Smith, Nakul Singh, Matt Murphy, Leroy Sibanda, Giovanni Traverso, Nevan C. Hanumara   +8 more
doaj   +1 more source

Minimizing topical medication in cataract surgery

TNOA Journal of Ophthalmic Science and Research, 2021
Cataract surgery requires the use of multiple topical eye drops application in the pre and postoperative period. Certain strategies offer the patient and surgeon assured drug delivery without topical eye drop instillation avoiding the pitfalls of patient
Sandip Sarkar, Nirupama Kasturi, Narayan Bardoloi   +2 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Patients’ Experience of Using Eye Drop Guide Device to Aid Self-Administration of Glaucoma Medications

Clinical Ophthalmology, 2020
Darin Sakiyalak, Sirinya Kobwanthanakun Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Darin SakiyalakDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol ...
Sakiyalak D, Kobwanthanakun S
doaj  

Epidemic Keratoconjunctivitis in Al-Ramadi City

مجلة كلية الطب, 2014
Background: Epidemic keratoconjunctivitis (EKC) is a viral conjunctivitis caused by a group of adenoviruses. EKC is highly contagious and has a tendency to occur in epidemics.
Zeina M. Al-Sabti
doaj   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Difficulties with self instillation of eye drops and its impact on intraocular pressure in glaucoma patients

Journal of Clinical Ophthalmology and Research, 2015
Aims: Prevalence of glaucoma increases with age and this potentially blinding condition requires regular instillation of eye drops. But with aging itself and accompanying co-morbidities, self instillation of eye drops gets affected.
Shalini Virani, Parveen Rewri, Murali Dhar   +2 more
doaj   +1 more source