Results 51 to 60 of about 12,899,024 (295)

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Visual status and prevalence of eye disorders among school-age children in southern Nigeria

African Vision and Eye Health, 2017
Aim: This study assessed the types and prevalence of eye problems among school-age children in Cross River State (CRS), Nigeria. Method: The study design was a cross-sectional analytic survey of 2418 school children aged 6–17 years from seven public and
Bernadine N. Ekpenyong, Kovin Naidoo, Kelechukwu Ahaiwe, Onyeka Ezenwankwo, Onyebuchi Ndukwe, Emmanuel Ogar, Ekanem Ekanem   +6 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Content validity of the nursing diagnosis proposal Ocular dryness in adult patients admitted to the intensive care unit

Enfermería Global
Objective: to verify the content validity of the nursing diagnosis proposal Ocular dryness in adult patients admitted to an intensive care unit. Materials and methods: this is a methodological study of content validation of the nursing diagnosis ...
Jéssica Naiara de Medeiros Araújo, Fabiane Rocha Botarelli, Ana Paula Nunes de Lima Fernandes, Ana Clara Dantas, Amanda Barbosa da Silva, Allyne Fortes Vitor   +5 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Helpful developments and technologies for school eye health programmes. [PDF]

, 2017
School eye health programmes provide a unique opportunity to positively influence the health of 700 million children globally. The impact of school eye health (SEH) goes far beyond good vision— it encompasses education, social development and economic ...
Morjaria, Priya, Bastawrous, Andrew, Andrew Bastawrous, Priya Morjaria   +3 more
core  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Refractive error correction and harvest worker productivity in the Guatemalan coffee sector: A quasi-experimental analysis

Global Public Health
Uncorrected refractive error - a condition affecting nearly 1 billion people globally - is a potentially significant constraint to economic productivity.
Bryce Everett, Andrew Hobbs, Brad Wong, Erwin Herdocia, Heidy Linares, Ana Marroquín, Juan Francisco Yee, K. Davina Frick, Travis J. Lybbert, Bruce Wydick   +9 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Teamwork for eye care [PDF]

, 2014
Human resource development (HRD) – the development of the people who deliver health care – has been identified as one of the key pillars of eye health delivery.
M Babar Qureshi
core