Results 71 to 80 of about 1,839,778 (304)

Perceptions of eye health in schools in Pakistan [PDF]

, 2006
BACKGROUND: Research exploring children's and their teachers' perceptions of eye health is lacking. This paper reports for the first time on perceptions of primary schoolchildren and their teachers of healthy and diseased eyes, things that keep eyes ...
Khabir Ahmad, Mohammad Aman Khan, Mohammad Daud Khan, Mohammad Babar Qureshi, Tanveer Anjum Chaudhry, Clare Gilbert, WHO, A Foster, H Limburg, SH Wedner, R Dandona, WHO, Unicef, Unicef, PI Paracha, A Molla, PM Kasi, BR Hughes, A Oakley, K Backett-Milburn, DT Williams, JM McWhirter, IA Pion, M Rademaker, E Sutter, PM Emerson, JA Kumaresan, D Mabey, J Schachter, GP Pokharel, H Limburg, ES West, PA Asbell, AA Awan, I Bozin, L Rothkoff, A Barr, L Dandona, J Lithander, JC Serrano, DA Goss, TY Wong, SA al-Hazzaa, AM Alkhawajah, A Hardy, C Parry, RL Canfield, RL Canfield   +47 more
core   +3 more sources

Emerging strategies to target metastasis and therapy resistance in melanoma

Molecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Priming of Pop-Out Does not Affect the Shooting Line Illusion [PDF]

, 1996
We combined a shooting-line illusion with a visual search pop-out task in an effort to determine whether priming of pop-out was due to acceleratcd processing of visual information in the primed dimension.
Gancarz, Gregory, Wolfe, Jeremy
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A Patient Centered Intervention to Promote Primary Care Based Screening for Diabetic Retinopathy [PDF]

, 2018
Diabetic Retinopathy is the leading cause of blindness in patient\u27s age 25-74 in the world. Onset of disease is insidious and early intervention is the only way to reduce morbidity.
Earle, William B
core   +1 more source

Is there overutilisation of cataract surgery in England? [PDF]

, 2009
<b>Objectives:</b> Following a 3.7-fold increase in the rate of cataract surgery in the UK between 1989 and 2004, concern has been raised as to whether this has been accompanied by an excessive decline in the threshold such that some ...
Black, N., Browne, J., Copley, L.P., Jamison, L., Lewsey, J., van der Meulen, J.H.   +5 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Construction and Validation of an Educational Technology to Promote the Health of Postmenopausal Women with Dry Eye Syndrome

European Journal of Investigation in Health, Psychology and Education
The climacteric heralds a transition from reproductive to non-reproductive life in women, often accompanied by various clinical manifestations such as dry eye, impacting their quality of life.
Álvaro Dantas de Almeida Junior, Italla Maria Pinheiro Bezerra, Sabrina Alaide Amorim Alves, Elisa Tristan-Cheever, Thiago Salati, Luiz Carlos de Abreu   +5 more
doaj   +1 more source

Eye Care Service in Scotland: Did the Scots Get it Right? [PDF]

, 2011
In March 2004, the Scottish government announced a review of eye care services in Scotland, which culminated in the introduction of free eye examinations from 1st April 2006.
Zangelidis, Alexandros
core