Results 61 to 70 of about 1,827,878 (305)

Digital ophthalmology in Scotland: benefits to patient care and education

open access: yesClinical Ophthalmology, 2019
Roxanne Annoh,1 Sirjhun Patel,2 Daniel Beck,1 Heather Ellis,3,4 Bal Dhillon,1,4 Roshini Sanders4,5 1Princess Alexandra Eye Pavilion, Edinburgh, UK; 2Ophthalmology Department, Ninewells Hospital, Dundee, UK; 3Ophthalmology Department, Lauriston Building,
Annoh R   +5 more
doaj  

Intelligent eye health analysis methods based on multimodal data fusion

open access: yes工程科学学报
In recent years, the issue of people’s vision has become increasingly important and has emerged as a social issue that has attracted widespread attention.
Kejiang XIAO   +4 more
doaj   +1 more source

ANALYSIS OF MYOPIA RISK FACTORS BY MACHINE LEARNING: APPLICATIONS AND IMPLICATIONS [PDF]

open access: yesProceedings on Engineering Sciences
Myopia, or near vision, is an increasingly common eye condition worldwide, particularly in East and Southeast Asia. This condition prevents individuals from seeing distant objects clearly, leading to functional and health impairments that can severely ...
Samya Korziti   +4 more
doaj   +1 more source

SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells [PDF]

open access: yes, 2009
Cochlear hair cells use SK2 currents to shape responses to cholinergic efferent feedback from the brain. Using SK2-/- mice, we demonstrate that, in addition to their previously defined role in modulating hair cell membrane potentials, SK2 channels are ...
Adelman, John P.   +8 more
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Kolaborasi Perguruan Tinggi dan IROPIN Tasikmalaya dalam Skrining Kesehatan Mata Masyarakat

open access: yesJurnal Nuansa Akademik
Eye health is an essential determinant of quality of life, particularly in rural communities where access to specialized medical services is often limited.
Cucu Nurpatonah   +9 more
doaj   +1 more source

Eye drop Self-medication: Comparative Questionnaire-based study of two Latin American cities. [PDF]

open access: yes, 2014
A broad spectrum of ocular symptoms are treated by self-medication with commercial eye-drops.  This behavior threatens individuals' visual health. In Latin America, evidence is poor.
Gramajo, Ana L.   +7 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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