When to consider an inborn error of immunity: clues for physicians
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
ABSTRACT Background Opportunistic yeasts account for a substantial proportion of invasive fungal infections and are important agents of healthcare‐associated infections, especially in intensive care units (ICUs). Objectives To describe the clinical and epidemiological characteristics of hospitalized patients with positive cultures for medically ...
Yasmim Passos Lima +8 more
wiley +1 more source
Tubulointerstitial Nephritis With Uveitis (TINU) Syndrome: A Case Series and Review of Literature
ABSTRACT Tubulointerstitial nephritis with uveitis (TINU) syndrome is a rare disorder characterised by the simultaneous or sequential occurrence of acute tubulointerstitial nephritis and uveitis, in the absence of systemic disease. Its true prevalence is likely underestimated, as renal and ocular manifestations may not appear concurrently. We conducted
Weaam Ali +5 more
wiley +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Equine Fungal Keratitis due to Cladorrhinum bulbillosum
ABSTRACT Objective To describe the case details and treatment of an equine fungal keratitis case caused by Cladorrhinum bulbillosum. Animal Studied A 14‐year‐old Bashkir Curly gelding with a complicated corneal ulcer of the left eye. Procedures Corneal cytology was performed, and intraoperative samples were collected for polymerase chain reaction and ...
Abigail Hamilton +2 more
wiley +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Peer review of the pesticide risk assessment of the active substance Beauveria bassiana strain R444
Abstract The conclusions of the EFSA following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State, Denmark, for the pesticide active substance Beauveria bassiana strain R444 and the considerations as regards the inclusion of the substance in Annex IV of Regulation (EC) No 396/2005 are ...
European Food Safety Authority (EFSA) +47 more
wiley +1 more source
Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies
A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga +5 more
wiley +1 more source
Related searches:
Voriconazole in the treatment of fungal eye infections: a review of current literature
British Journal of Ophthalmology, 2008Voriconazole has an important role to play in the prophylaxis and management of fungal endophthalmitis and keratitis. New-generation triazoles, including voriconazole, posaconazole and ravuconazole, have been shown in laboratory studies and clinical experience to have very good safety profiles with few side effects.
J R Graybill
exaly +3 more sources
Fungal Eye Infections: New Hosts, Novel Emerging Pathogens but No New Treatments?
Current Fungal Infection Reports, 2018We sought to explore the current incidence and associated risk factors associated with fungal eye infections. We also reviewed new diagnostic strategies and recent clinical studies exploring the use of topical and oral antifungal agents. Incidence and associated risks continue to vary with geographic region, and access to timely healthcare.
Sharon Chen
exaly +2 more sources

