Results 11 to 20 of about 28,460 (261)

Preliminary Study on an Alternative Test Method with MCTT HCE^TM for Ocular Irritation Test of Ophthalmic Medical Devices

Toxics, 2023
The sustained growth of the market for ophthalmic medical devices has increased the demand for alternatives to animal testing for the evaluation of eye irritation.
Yang-Jee Kim, Dong-Hyuk Seo, Il-Soo Kim, Mi-Sook Jung, Jin-Young Bae, Moon-Yong Song, Kyung-Seuk Song, Jin-Sik Kim   +7 more
doaj   +1 more source

TiO2 Nanoparticles as a Common Component of Sunscreens: An Experimental Study of Dermal/Ocular Safety Assessment [PDF]

Iranian Journal of Veterinary Medicine, 2019
Background: The safety evaluations of sunscreens containing Titanium Dioxide-Nanoparticles (TiO2-NPs) were done by dermal exposure, acute dermal and eye irritation/corrosion, and skin sensitization according to the guideline for Organization for Economic
Seyedeh Maedeh Jafari, Goudarz Sadeghi Hashtjin, Mohammad Kazem Koohi, Ali Rasooli, Ebrahim Shahroozian   +4 more
doaj   +1 more source

Eye Irritation Test of Bovis Calculus Pharmacopuncture Solutions for Eye Drop

Journal of Pharmacopuncture, 2008
Objective : This study was done to investigate the safety of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop.
Hyeong-sik Seo
doaj   +1 more source

Eye Irritation Test of Fel Ursi Pharmacopuncture Solutions for Eye Drop

Journal of Pharmacopuncture, 2008
Objective : This study was done to investigate the safety of Fel Ursi pharmacopuncture solution manufactured with freezing dryness method to use eye drop.
Hyeong-sik Seo
doaj   +1 more source

Alternative methods for the replacement of eye irritation testing

ALTEX, 2016
In the last decades significant regulatory attempts were made to replace, refine and reduce animal testing to assess the risk of consumer products for the human eye. As the original in vivo Draize eye test has been criticized for limited predictivity, costs and ethical issues, several animal-free test methods have been developed to categorize ...
Lotz, Christian, Schmid, Freia F., Rossi, Angela, Kurdyn, Szymon, Kampik, Daniel, De Wever, Bart, Walles, Heike, Groeber, Florian K.   +7 more
openaire   +4 more sources

Characterization of new eye drops with choline salicylate and assessment of their irritancy by in vitro short time exposure tests

Saudi Pharmaceutical Journal, 2014
The aim of our study was to examine the irritation potential of new eye drops containing 2% choline salicylate (CS) as an active pharmaceutical ingredient (API) and various polymers increasing eye drop viscosity (hydroxyethylcellulose, hydroxypropyl ...
Katarzyna Wroblewska, Małgorzata Kucinska, Marek Murias, Janina Lulek   +3 more
doaj   +1 more source

Eye Irritation Test of Fel Ursi & Bovis Calculus Pharmacopuncture Solutions for Eye Drop

Journal of Pharmacopuncture, 2008
Objective : This study was done to investigate the safety of Fel Ursi & Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods : The eye irritation test of this material was performed according to the
Hyeong-sik Seo
doaj   +1 more source

The Experimental study of safety and efficacy in using Soyeom Pharmacopuncture solution as eyedrops

Journal of Pharmacopuncture, 2009
Objective : This experimental study was performed to investigate the safety of Soyeom Pharmacopunture solution manufactured by extraction of alcohol and water.
Eun-Kyo Kang, Hyung-sik Seo
doaj   +1 more source

Cyclosporine Lipid Nanocapsules as Thermoresponsive Gel for Dry Eye Management: Promising Corneal Mucoadhesion, Biodistribution and Preclinical Efficacy in Rabbits

Pharmaceutics, 2021
An ophthalmic cyclosporine (CsA) formulation based on Lipid nanocapsules (LNC) was developed for dry eye management, aiming to provide targeting to ocular tissues with long-term drug levels and maximum tolerability.
Lubna M. Eldesouky, Riham M. El-Moslemany, Alyaa A. Ramadan, Mahmoud H. Morsi, Nawal M. Khalafallah   +4 more
doaj   +1 more source

Ocular surface and tear film changes in workers exposed to organic solvents used in the dry-cleaning industry.

PLoS ONE, 2019
Workers in the dry-cleaning industry are exposed to organic solvents that may cause eye irritation and tear film changes. Objective To quantify changes in the ocular surface and tear film in dry cleaners exposed to organic solvents and associate these ...
Ingrid Astrid Jiménez Barbosa, Martha Fabiola Rodríguez Alvarez, Gerardo Andrés Dussán Torres, Sieu K Khuu   +3 more
doaj   +1 more source