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Assessment of the feed additive consisting of inositol (3a900) for fish and crustaceans for the renewal of its authorisation (Zhucheng Haotian Pharm Co., Ltd.). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Röhe I, Theodoridou K, Woutersen R, Galobart J, Manini P, Pizzo F, Radovnikovic A, Vettori MV, Gkimprixi E.   +23 more
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High-Frequency Application of Cationic Agents Containing Lubricant Eye Drops Causes Cumulative Corneal Toxicity in an Ex Vivo Eye Irritation Test Model.

Journal of Ocular Pharmacology and Therapeutics, 2020
Purpose: High-frequency applied cetalkonium chloride (CAC) and benzalkonium chloride (BAC) 0.02% did not hamper corneal healing in a living rabbit model of induced corneal erosion.
R. Dutescu, D. Uthoff, C. Panfil, N. Schrage   +3 more
semanticscholar   +1 more source

Multi-laboratory Validation Study of the Vitrigel-Eye Irritancy Test Method as an Alternative to In Vivo Eye Irritation Testing

Alternatives to laboratory animals : ATLA, 2019
Collagen vitrigel membranes (CVMs) comprising high-density collagen fibrils equivalent to in vivo connective tissues have been widely used in cell culture applications. A human corneal epithelium (hCE) model was previously developed by the Takezawa group,
H. Kojima, Hiroyuki Yamaguchi, T. Sozu, N. Kleinstreuer, Lim Chae-Hyung, Wannhsin Chen, Mika Watanabe, T. Fukuda, Kunihiko Yamashita, T. Takezawa   +9 more
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Comparison of the different protocols of the Hen's Egg Test-Chorioallantoic Membrane (HET-CAM) by evaluating the eye irritation potential of surfactants.

Toxicology in Vitro, 2021
Luciana Madureira de Araujo Lowndes Viera, R. Silva, Cristiane Caldeira da Silva, O. Presgrave, M. H. Boas   +4 more
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TG 494: Vitrigel-Eye Irritancy Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage

OECD Guidelines for the Testing of Chemicals, Section 4, 2021

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SkinEthic HCE Time-to-Toxicity on solids: A test method for distinguishing chemicals inducing serious eye damage, eye irritation and not requiring classification and labelling.

Toxicology in Vitro, 2021
N. Alépée, V. Leblanc, M. Grandidier, S. Teluob, A. Viricel, E. Adriaens, V. Michaut   +6 more
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Me-too validation study for in vitro eye irritation test with 3D-reconstructed human cornea epithelium, MCTT HCETM.

Toxicology in Vitro, 2019
Song-E Lim, Su Ha, Won-hee Jang, K. Jung, M. Jung, Kyung-Wook Yeo, Jin-Sik Kim, T. Jeong, M. Kang, Seolyeong Kim, Su-Hyun Lee, K. Ko, Tae-Sung Kim, K. Park, S. Bae, Kyung-Min Lim   +15 more
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Development and validation of UPLC method for WST-1 cell viability assay and its application to MCTT HCE™ eye irritation test for colorful substances.

Toxicology in Vitro, 2019
Kyung-Mi Joo, Seolyeong Kim, Y. Koo, Miri Lee, Su-Hyun Lee, Dalwoong Choi, Kyung-Min Lim   +6 more
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The Ex vivo Eye Irritation Test (EVEIT) model as a mean of improving venom ophthalmia understanding

Toxicon, 2018
M. Delafontaine, C. Panfil, F. Spöler, S. Kray, François Burgher, L. Mathieu, J. Blomet, N. Schrage, D. Tambourgi   +8 more
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CON4EI: EpiOcular™ Eye Irritation Test (EpiOcular™ EIT) for hazard identification and labelling of eye irritating chemicals.

Toxicology in Vitro, 2017
Helena Kandarova, S. Letašiová, E. Adriaens, R. Guest, J. Willoughby, A. Drzewiecka, K. Gruszka, N. Alépée, S. Verstraelen, A. V. Rompay   +9 more
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