Results 121 to 130 of about 105,778 (297)

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Eye Neoplasm [PDF]

, 2020
openaire   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Intraocular Sarcomas in Two Rabbits

, 2009
Intraocular neoplasms are described in 2 adult rabbits. The left globe of an 8-year-old male rabbit was enucleated after chronic inflammatory disease resulted in a nonvisual eye.
Leslie McPherson, Nancy McLean, Stephen Kania, Ramesh Vemulapalli, Stephanie McCain, Richard R. Dubielzig, Shelley J. Newman   +6 more
core   +1 more source

Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy

Advanced Science, EarlyView.
A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li, Ruixiao Hu, Jie Mao, Jin Wo, Yunsong Zhang, Liang Chen, Ying Liu, Zhibo Li, Yongxin Lin, Minghui Du, Yaofei Chen, Libing Zhou, Tuan Guo   +12 more
wiley   +1 more source

Uso tópico do inteferon alfa-2b para neoplasia escamosa da superficie ocular em um caso de paciente com xeroderma pigmentoso

Revista Brasileira de Oftalmologia
Resumo Relato de um caso clínico de Xeroderma Pigmentoso com carcinoma espinocelular de conjuntiva bilateral que apresentou regressão importante das dimensões tumorais com o uso de Interferon alfa-2b tópico.
Nayara Queiroz Cardoso Pinto, Jhonatan de Paula Araujo Ferreira, Gustavo Jose Arruda Mendes Carneiro, Jailton Vieira Silva, Luanna Biana Costa Bezerra, Natália Ponte Nogueira   +5 more
doaj   +1 more source

Metastatic hemangiosarcoma in canine eye: proton and sodium MRI with histological correlation

, 1995
In this study proton and sodium magnetic resonance imaging were performed on an apparently healthy eye of a dog with metastatic haemangiosarcoma in order to compare image featured with histological findings. A fresh globe was removed at PM from a 13-year-
Marciani, L., Cammarata, G., Boicelli, A., Mertel, L., Baldassarri, A. M.   +4 more
core  

Detection of Asymmetric Blotches (asymmetric Structureless Areas) in Dermoscopy Images of Malignant Melanoma using Relative Color

, 2005
Dermoscopy, also known as dermatoscopy or epiluminescence microscopy (ELM), is a non-invasive, in vivo technique, which permits visualization of features of pigmented melanocytic neoplasms that are not discernable by examination with the naked eye.
Stoecker, William V., William V. Stoecker, Randy H. Moss, Gupta, Kapil, Moss, Randy Hays, Shrestha, Bijaya, Kapil Gupta, Bijaya Shrestha, Stanley, R. Joe, R. Joe Stanley   +9 more
core   +1 more source

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

Advanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu, Yunlong Li, Hanmeng Liu, Peng Zhang, Mingjing Wang, Quanwei Sun, Wenshuo Yang, Zhengwei Song, Song Tan, Ye Yang, Peng She, Dengke Yin, Wei Shen   +12 more
wiley   +1 more source

Retinoblastoma in a six-year-old girl

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Retinoblastoma is a hereditary malignant tumor of the retina in children and is generally diagnosed before the age of 5. This study presents the clinical case of a 6-year-old girl who came to the department of ophthalmology of Malanje Hospital, Angola ...
Elizabeth Ramírez Pérez, Adriana Abreu Leyva   +1 more
doaj