Results 111 to 120 of about 808,416 (295)
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh +2 more
wiley +1 more source
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
This entry includes three infographics (in Sinhala) and no writeups.On 31st October 2023, the Ethics Eye team published a three-slide post as part of their "Ethic of the Week" series.
Ethics Eye
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BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai +7 more
wiley +1 more source
Extraskeletal osteosarcoma arising in the globe of an irradiated, heritable retinoblastoma survivor
Purpose: Individuals with hereditary retinoblastoma (RB) carry a heightened risk of developing subsequent malignant neoplasms that is amplified by prior radiation treatment.
Joana E. Andoh +9 more
doaj +1 more source
This entry includes a write-up and an infographic (both in Sinhala).On January 25, 2024, Ethics Eye posted a post showing the front page headlines from Sinhala and English newspapers about the passing of the Online Safety Bill.
Ethics Eye
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AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang +21 more
wiley +1 more source
Temporal lobe tumor presenting as isolated third nerve palsy
Many etiologies have been associated with isolated third nerve palsies. They are ischemic microangiopathy, posterior communicating artery aneurysm, uncal herniation, neoplasms, trauma, and inflammatory conditions.
OU Mallika, Alisha P Shaju
doaj +1 more source
Disability: recommendations for eye programmes [PDF]
In 2012, CBM’s Medical Eye Care Advisory Working Group met in Hyderabad, India to discuss the inclusion of people with disabilities in eye care.As a result of these discussions, recommendations were ...
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