Results 81 to 90 of about 124,209 (305)

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez   +8 more
wiley   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Sociodemographic, clinical, epidemiological and care aspects of children and adolescents treated for retinoblastoma in Brazil

open access: yesMedicina, 2022
Introduction: Retinoblastoma greatly impacts the affected children and adolescents and their families. Epidemiological approaches to this form of cancer in Brazil are scarce, and this gap motivated this study.
Gabriela Silva Bochi   +6 more
doaj  

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles [PDF]

open access: yes, 1996
Notch is a highly conserved transmembrane protein that is involved in cell fate decisions and is found in organisms ranging from Drosophila to humans. A human homologue of Notch, TAN1, was initially identified at the chromosomal breakpoint of a subset of
Aster, Jon C.   +6 more
core  

Increased risk for other cancers in individuals with Ewing sarcoma and their relatives. [PDF]

open access: yes, 2019
BackgroundThere are few reports of the association of other cancers with Ewing sarcoma in patients and their relatives. We use a resource combining statewide genealogy and cancer reporting to provide unbiased risks.MethodsUsing a combined genealogy of 2 ...
Abbott, Diana   +9 more
core   +1 more source

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

open access: yesAdvanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou   +4 more
wiley   +1 more source

Orbito-ocular tumours in Nigeria adults: A review of 94 patients over a period of 11 years

open access: yesInternational Journal of Medicine and Health Development, 1997
We present a review of histologically confirmed tumours of the eye and adnexa in 94 Nigerian adults at the University of Nigeria Teaching Hospital, Enugu, from 1980 to 1990. The neoplasms in 50% of the patients (26 male.
Chimdi M Ekwerekwu   +2 more
doaj  

Long-term survival in a patient with unresectable liver metastases from uveal melanoma treated with transarterial chemoembolization with irinotecan eluting beads – case report and review of literature

open access: yesContemporary Oncology, 2017
Introduction : Treatment of unresectable liver metastases (LM) from uveal melanoma (UM) remains a major clinical challenge. Systemic chemotherapy and chemoimmunotherapy regimens extrapolated from cutaneous melanoma are considered to be ineffective in ...
Katarzyna Stanisławska   +5 more
doaj   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

A Rare Case of Intraconal Orbital Schwannoma

open access: yesArchives of Medicine and Health Sciences
Schwannoma is a benign, slow-growing peripheral nerve sheath tumor that originates from Schwann cells. Orbital schwannoma is relatively rare, accounting for only 1% of all orbital neoplasms. Intraconal orbital schwannoma (within the muscle cone) is rarer
Savithri Ravindra   +2 more
doaj   +1 more source

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