Results 81 to 90 of about 124,209 (305)
Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez +8 more
wiley +1 more source
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Introduction: Retinoblastoma greatly impacts the affected children and adolescents and their families. Epidemiological approaches to this form of cancer in Brazil are scarce, and this gap motivated this study.
Gabriela Silva Bochi +6 more
doaj
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles [PDF]
Notch is a highly conserved transmembrane protein that is involved in cell fate decisions and is found in organisms ranging from Drosophila to humans. A human homologue of Notch, TAN1, was initially identified at the chromosomal breakpoint of a subset of
Aster, Jon C. +6 more
core
Increased risk for other cancers in individuals with Ewing sarcoma and their relatives. [PDF]
BackgroundThere are few reports of the association of other cancers with Ewing sarcoma in patients and their relatives. We use a resource combining statewide genealogy and cancer reporting to provide unbiased risks.MethodsUsing a combined genealogy of 2 ...
Abbott, Diana +9 more
core +1 more source
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou +4 more
wiley +1 more source
Orbito-ocular tumours in Nigeria adults: A review of 94 patients over a period of 11 years
We present a review of histologically confirmed tumours of the eye and adnexa in 94 Nigerian adults at the University of Nigeria Teaching Hospital, Enugu, from 1980 to 1990. The neoplasms in 50% of the patients (26 male.
Chimdi M Ekwerekwu +2 more
doaj
Introduction : Treatment of unresectable liver metastases (LM) from uveal melanoma (UM) remains a major clinical challenge. Systemic chemotherapy and chemoimmunotherapy regimens extrapolated from cutaneous melanoma are considered to be ineffective in ...
Katarzyna Stanisławska +5 more
doaj +1 more source
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
A Rare Case of Intraconal Orbital Schwannoma
Schwannoma is a benign, slow-growing peripheral nerve sheath tumor that originates from Schwann cells. Orbital schwannoma is relatively rare, accounting for only 1% of all orbital neoplasms. Intraconal orbital schwannoma (within the muscle cone) is rarer
Savithri Ravindra +2 more
doaj +1 more source

