Results 31 to 40 of about 715 (161)
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu +20 more
wiley +1 more source
Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li +9 more
wiley +1 more source
Non-invasive in vivo fluorescence imaging of apoptotic retinal photoreceptors
Phosphatidylserine externalization is an early molecular signature for apoptosis. In many retinal degenerative diseases, photoreceptor neurons die by apoptosis.
Francesca Mazzoni +5 more
doaj +1 more source
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud +14 more
wiley +1 more source
Abstract Purpose To evaluate real‐world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age‐related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals, patients with nAMD at a Danish tertiary retina clinic were systematically switched to aflibercept 8 mg ...
Mary Graciya Karunainathan +12 more
wiley +1 more source
The efficacy of conjunctiva coverage in combination with amnion liquid supernatant eye drop on deep layer corneal ulcer in canine caused by alkali burn combined with mechanical injury [PDF]
The purpose of this study was to establish the model of canine deep layer corneal ulcer by means of alkali burn combined with mechanical injury and evaluate the efficacy of conjunctival covering combined with amnion liquid supernatant deep layer corneal ...
Jiasan ZHENG +6 more
doaj +1 more source
Abstract Purpose To estimate the real‐world incidence of intraocular inflammation (IOI) following intravitreal faricimab injections at a large, highly specialized tertiary centre. Methods Single‐centre, retrospective cohort study with chart review using an electronic injection database and electronic medical records from November 2023 to August 2024 ...
Miklos Schneider +7 more
wiley +1 more source
Female BALB/c mice were given PBS (△) or H1N1 split vaccine Ag alone (eyedrop, ○; IN, □) or Ag plus 10 μg poly(I:C) (eyedrop, ●; IN, ■) by eyedrop or IN two times at a 2-week interval.
Eun-Do Kim (599727) +6 more
core +1 more source
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen +9 more
wiley +1 more source
Representative H&E stained corneal tissue sections showing toxicity and efficacy in vivo.
Corneal sections of naive Group-2 (A), unwounded eyedrop-treated Group-4 (B), alkali wounded Group-1 (C), and alkali wounded and eyedrop-treated Group-4 (D) eyes. Group-2 (A) and Group-4 corneas showed normal corneal morphology.
Rajiv R. Mohan (11927137) +4 more
core +1 more source

