Results 71 to 80 of about 5,091 (258)
Advanced Science, EarlyView.During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang +8 more
wiley +1 more source
Evolution of Physical Intelligence Across Scales
Advanced Intelligent Discovery, EarlyView.By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.The engineered DTSe‐based photosensitizer, DZTSe, emerges as an avant‐garde molecular entity, which can distribute to both the endoplasmic reticulum and mitochondria to concurrently trigger pyroptosis and activate the cGAS‐STING pathway. This dual‐action strategy effectively reprograms the tumor microenvironment, enabling potent eradication of primary ...
Cheng Zhang +7 more
wiley +2 more sources
Cteno‐Bot: An Untethered Metachronally Swimming Robot With Magnetoactive Propulsors
Advanced Intelligent Systems, EarlyView.We present Cteno‐bot, an untethered ctenophore‐inspired robot which swims using metachronally coordinated appendages. A single mechanism controls up to 216 magnetoactive propulsors via a dynamically varying magnetic field. We show that the swimming speed of the robot can be increased without a corresponding increase in power requirement, simply by ...
David J. Peterman, Margaret L. Byron
wiley +1 more source
Small‐Scale Magnetic Peristaltic Soft Robot With Mobility and Transport Capabilities
Advanced Intelligent Systems, EarlyView.This study introduces a miniature, untethered soft magnetic microrobot with peristaltic capabilities for both locomotion and cargo transport. Eight helically magnetized elastomeric strips deform under rotating fields (10–80 mT, 1–5 Hz), enabling movement across rods and lumina at up to 4.1 body lengths min‐¹.
Mohammad Hasan Dad Ansari +4 more
wiley +1 more source
Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy +16 more
wiley +1 more source
Australian and New Zealand Journal of Ophthalmology, 1991 F P, English +4 more
openaire +2 more sources
Hypothyroidism, eyelash loss [PDF]
Cleveland Clinic Journal of Medicine, 2020 Hiroki, Matsuura, Yu, Suganami
openaire +2 more sources
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew +8 more
wiley +1 more source
Frontiers in Aging NeuroscienceBackgroundCognitive impairment in the elderly may lead to potential increased sensitivity to anesthetic agents targeting receptors associated with cognition.
Huiting Zhuge +3 more
doaj +1 more source