Results 221 to 230 of about 43,675 (258)

Epigenetic Targeting with EZH2 and HDAC Inhibitors Is Synergistic in EZH2 Deregulated Lymphomas

Blood, 2016
Abstract EZH2 is critical in a process known as the Germinal Center (GC) reaction during which B-cells undergo somatic hypermutation and isotype switching in order to develop a large antibody repertoire. EZH2 is a histone methyltransferase serving as the catalytic subunit of the Polycomb Repression Complex 2 (PRC2), which is responsible ...
Jennifer Kimberly Lue, Sathyen A Prabhu, Yuxuan Liu, Owen A. O'Connor, Jennifer E Amengual   +4 more
openaire   +1 more source

Targeting EZH2 with tazemetostat

The Lancet Oncology, 2018
Shinichi, Makita, Kensei, Tobinai
openaire   +2 more sources

EZH2 Goes Solo

Science, 2012
A transcriptional repressor switches to an activator function in an aggressive form of prostate cancer.
openaire   +1 more source

SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways

Cancer Cell, 2020
Jun Jiang, Jun Qin, Minjia Tan
exaly  

Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response

Cancer Cell, 2020
Katsuyoshi Takata, Matt Teater, Jeannie Camarillo   +2 more
exaly  

EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition

Cancer Cell, 2020
Jianhuang Lin, Bo Zhao, Nail Fatkhutdinov   +2 more
exaly  

Targeting EZH2 for cancer therapy: From current progress to novel strategies

European Journal of Medicinal Chemistry, 2022
Liang Ouyang, Ji Fa Zhang, Yuxi Wang
exaly  

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis

Cancer Cell, 2017
Charles Rüdin, Natasha Rekhtman, John Poirier   +2 more
exaly  

EZH2 Gene

2020
openaire   +1 more source

N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer

Cancer Cell, 2016
Brian Robinson, Andrea Sboner, David Rickman   +2 more
exaly