A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium [PDF]
Genome BiologyBackground The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2).
Thomas Balan +9 more
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Inexpensive protocol for single-cell X-chromosome inactivation analysis: Xist expression and H3K27me3 staining [PDF]
Письма в Вавиловский журнал генетики и селекции, 2022 The X-chromosome status is an important marker of mammalian cell embryonic differentiation. Both female X-chromosomes are transcriptionally active (Xa) at the blastocyst stage, then one of the X-chromosomes undergoes random inactivation (Xi).
Pristyazhnyuk I.E. +2 more
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Expression of H3K27me3 in Tibetan Patients with Gastric Cancer and Its Significance
Xiehe Yixue Zazhi, 2022 Objective To investigate the expression and its significance of H3K27me3 in Tibetan patients with gastric cancer. Methods Clinical and pathological data were retrospectively collected from Tibetan patients with gastric cancer in the Tibet Autonomous ...
LUO Hanhuan +9 more
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Expression of EZH2 and H3K27me3 predicts tumor biology of urothelial carcinoma
Indian Journal of Pathology and Microbiology, 2023 Background: Enhancer of zeste homolog 2 (EZH2) is one of the major epigenetic modifiers involved in the transcriptional repression of target genes through trimethylation of H3K27 (lysine 27 residue of histone H3).
Rasheeda Mohamedali +5 more
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Expression and clinical significance of H3K27me3 in hemangioma and vascular malformation
陆军军医大学学报, 2022 Objective To investigate the expression and clinical significance of H3K27me3 in vascular hemangioma and malformation. Methods Paraffin-embedded tissue blocks from 244 patients with hemangioma and vascular malformation admitted in our hospital from ...
WANG Junlan +4 more
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Genome-Wide Analysis of H3K27me3 in Porcine Embryonic Muscle Development
Frontiers in Cell and Developmental Biology, 2021 The trimethylation of histone H3 lysine 27 (H3K27me3) is one of the most important chromatin modifications, which is generally presented as a repressive mark in various biological processes.
Baohua Tan +20 more
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Activation of epigenetic regulator KDM6B by Salmonella Typhimurium enables chronic infections
Gut Microbes, 2021 Non-typhoidal Salmonella (NTS) infections result in self limiting gastroenteritis except in rare cases wherein manifestations of chronic infections can occur.
Sarika Rana +9 more
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Histone H1 facilitates restoration of H3K27me3 during DNA replication by chromatin compaction
Nature Communications, 2023 During cell renewal, epigenetic information needs to be precisely restored to maintain cell identity and genome integrity following DNA replication.
Cuifang Liu +7 more
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mBio, 2022 Differential growth conditions typically trigger global transcriptional responses in filamentous fungi. Such fungal responses to environmental cues involve epigenetic regulation, including chemical histone modifications.
H. Martin Kramer +3 more
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Epigenetics, 2019 Enhancer of zeste homolog 2 (EZH2), a component of the PRC2 complex, trimethylates H3K27, a transcriptionally repressive histone mark. EZH2 is encoded by a dormant maternal mRNA and inhibiting the maturation-associated increase in EZH2 activity using ...
Huili Wang +4 more
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