Results 1 to 10 of about 189,008 (259)
Scientific Reports, 2023 Human epidermal growth factor receptor 2 (HER2) plays an important role in diagnosis and treatment of breast cancer (BRCA). The histone modification has been found to be related to the progression of cancer.
Jia Li, Jingchun Yao, Liqiang Qi
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BMC Biology, 2004 Background In mammals, there is evidence suggesting that methyl-CpG binding proteins may play a significant role in histone modification through their association with modification complexes that can deacetylate and/or methylate nucleosomes in the ...
Canfield Theresa K +6 more
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Histone modifications centric-regulation in osteogenic differentiation
Cell Death Discovery, 2021 Histone modification critically contributes to the epigenetic control of gene expression by changing the configuration of chromatin and modifying the access of transcription factors to gene promoters.
Kun Li, Jinxiang Han, Ziqiang Wang
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SnapShot: Histone Modifications
Cell, 2014 Histone proteins are decorated by a variety of protein posttranslational modifications called histone marks that modulate chromatin structure and function, contributing to the cellular gene expression program. This SnapShot summarizes the reported human, mouse, and rat histone marks, including recently identified lysine acylation marks.
Huang, He +4 more
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ChIP-seq profiling of H3K4me3 and H3K27me3 in an invasive insect, Bactroceradorsalis
Frontiers in Genetics, 2023 Introduction: While it has been suggested that histone modifications can facilitate animal responses to rapidly changing environments, few studies have profiled whole-genome histone modification patterns in invasive species, leaving the regulatory ...
Yan Zhao +3 more
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Frontiers in Oncology, 2019 IPO-38 is a potential biomarker for early diagnosis of gastric cancer that we recently identified. Although we characterized its chemical nature as a nucleosome histone, we suspected the existence of histone modification for the IPO-38 antibody-labeled ...
Shuzheng Song +6 more
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Histone modification in Drosophila [PDF]
Briefings in Functional Genomics, 2012 Post-translational modifications (PTMs) of nucleosomal core histones play roles in basic biological processes via altering chromatin structure and creating target sites for proteins acting on chromatin. Several features make Drosophila a uniquely effective model for studying PTMs.
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Finding combinatorial histone code by semi-supervised biclustering
BMC Genomics, 2012 Background Combinatorial histone modification is an important epigenetic mechanism for regulating chromatin state and gene expression. Given the rapid accumulation of genome-wide histone modification maps, there is a pressing need for computational ...
Teng Li, Tan Kai
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Scientific Reports, 2022 Post-translational modification of histones is the crucial event that affect many tumor-specific traits. A diverse type of histone modifications had been reported in different cancers with prognostic implications.
Aroonwan Lam-Ubol +1 more
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Chromatin changes in response to drought, salinity, heat, and cold stresses in plants
Frontiers in Plant Science, 2015 Chromatin regulation is essential to regulate genes and genome activities. In plants, the alteration of histone modification and DNA methylation are coordinated with changes in the expression of stress-responsive genes to adapt to environmental changes ...
Jong-Myong eKim +8 more
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