Results 41 to 50 of about 1,112,729 (199)

Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms [PDF]

, 2007
Alteration of chromatin structure by chromatin modifying and remodelling activities is a key stage in the regulation of many nuclear processes. These activities are frequently interlinked, and many chromatin remodelling enzymes contain motifs that ...
Owen-Hughes, Tom; id_orcid, Flaus, Andrew, Ferreira, Helder, Owen-Hughes, Tom   +3 more
core   +1 more source

H3 Lysine 4 Is Acetylated at Active Gene Promoters and Is Regulated by H3 Lysine 4 Methylation [PDF]

, 2011
Methylation of histone H3 lysine 4 (H3K4me) is an evolutionarily conserved modification whose role in the regulation of gene expression has been extensively studied.
Richard J. Festenstein, Bonneil, Eric, Guillemette Benoit, Festenstein Richard J., Armstrong Harry, Festenstein, Richard J., Harry Armstrong, Imhof Axel, Armstrong, Harry, Richard J Festenstein, Drogaris, Paul, Axel Imhof, Verreault Alain, Kyoko Hiragami-Hamada, Drogaris Paul, Verreault, Alain, Benoit Guillemette, Thibault Pierre, Pierre Thibault, Lin Hsiu-Hsu Sophia, Hiragami-Hamada, Kyoko, Alain Verreault, Imhof, Axel, Paul Drogaris, Hsiu-Hsu Sophia Lin, Bonneil Éric, Eric Bonneil, Festenstein, Richard J, Hiragami-Hamada Kyoko, Guillemette, Benoit, Lin, Hsiu-Hsu Sophia, Thibault, Pierre   +31 more
core   +1 more source

A Novel Citrullinated Modification of Histone 3 and Its Regulatory Mechanisms Related to IPO-38 Antibody-Labeled Protein

Frontiers in Oncology, 2019
IPO-38 is a potential biomarker for early diagnosis of gastric cancer that we recently identified. Although we characterized its chemical nature as a nucleosome histone, we suspected the existence of histone modification for the IPO-38 antibody-labeled ...
Shuzheng Song, Zhen Xiang, Jun Li, Jun Ji, Ranlin Yan, Zhenggang Zhu, Yingyan Yu   +6 more
doaj   +1 more source

Histone modification in Drosophila [PDF]

Briefings in Functional Genomics, 2012
Post-translational modifications (PTMs) of nucleosomal core histones play roles in basic biological processes via altering chromatin structure and creating target sites for proteins acting on chromatin. Several features make Drosophila a uniquely effective model for studying PTMs.
openaire   +2 more sources

Global Analysis of the Relationship between JIL-1 Kinase and Transcription [PDF]

, 2010
The ubiquitous tandem kinase JIL-1 is essential for Drosophila development. Its role in defining decondensed domains of larval polytene chromosomes is well established, but its involvement in transcription regulation has remained controversial.
Regnard Catherine, Peter B Becker, Mitterweger Angelika, Ina K. Dahlsveen, Becker Peter B., Tobias Straub, Straub, Tobias, Peter B, Regnard, Catherine, Fabian Viola, Mitterweger, Angelika, Ina K Dahlsveen, Peter B. Becker, Dahlsveen Ina K., Becker, Peter B., Fabian, Viola, Dahlsveen, Ina K., Catherine Regnard, Angelika Mitterweger, Viola Fabian, Straub Tobias   +20 more
core   +2 more sources

Finding combinatorial histone code by semi-supervised biclustering

BMC Genomics, 2012
Background Combinatorial histone modification is an important epigenetic mechanism for regulating chromatin state and gene expression. Given the rapid accumulation of genome-wide histone modification maps, there is a pressing need for computational ...
Teng Li, Tan Kai
doaj   +1 more source

The histone H3 lysine 36 methyltransferase HypB facilitates embryonic stem cell differentiation [PDF]

, 2007
Histone H3 lysine 36 (H3K36) methylation was identified as a conserved modification from yeast to human. In yeast, biochemical characterization of the SET2 protein and genome wide mapping of H3K36me2 and K36me3 indicate that H3K36 methylation functions ...
Wang, Tianke
core   +1 more source

Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution [PDF]

, 2010
It has recently been shown that nucleosome distribution, histone modifications and RNA polymerase II (Pol II) occupancy show preferential association with exons (“exon-intron marking”), linking chromatin structure and function to co-transcriptional ...
Ellis Peter, Foad, NS, Christoph M Koch, Saffrey Peter, Dillon, SC, Alexander W Bruce, Dunham Ian, Bruce, A.W., Christoph M. Koch, Shane C. Dillon, Ellis, P, Saffrey, P., Chiang, K., Bye, J., Saffrey, P, James, K, James Keith, Watkins Nicholas A., Dhami, P., Watkins, N.A., Nicholas A. Watkins, Langford, C., Andrews, R.M., Dhami, P, Watkins, NA, Alexander W. Bruce, Bonhoure Nicolas, David Vetrie, Langford, C, Willem H Ouwehand, Chiang Kelly, Langford Cordelia, James, K., Pawandeep Dhami, Dunham, I., Vetrie David, Peter Saffrey, Bye, J, Ouwehand, W.H., Kelly Chiang, Foad Nicola S., Bonhoure, N, Andrews, RM, Willem H. Ouwehand, Shane C Dillon, Nicholas A Watkins, Cordelia Langford, Jackie Bye, Vetrie, D., Koch Christoph M., Bonhoure, N., Nicola S Foad, Koch, CM, Robert M Andrews, Keith James, Peter Ellis, Chiang, K, Ian Dunham, Dillon, S.C., Bruce Alexander W., Andrews Robert M., Dunham, I, Robert M. Andrews, Bye Jackie, Vetrie, D, Foad, N.S., Ellis, P., Bruce, AW, Ouwehand Willem H., Nicolas Bonhoure, Nicola S. Foad, Koch, C.M., Dillon Shane C., Ouwehand, WH, Wutz, A., Dhami Pawandeep   +75 more
core   +2 more sources

SnapShot: Histone Modifications

Cell, 2014
Histone proteins are decorated by a variety of protein posttranslational modifications called histone marks that modulate chromatin structure and function, contributing to the cellular gene expression program. This SnapShot summarizes the reported human, mouse, and rat histone marks, including recently identified lysine acylation marks.
Huang, He, Sabari, Benjamin R., Garcia, Benjamin A., Allis, C. David, Zhao, Yingming   +4 more
openaire   +2 more sources

Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity [PDF]

, 2011
Genomic maps of chromatin modifications have provided evidence for the partitioning of genomes into domains of distinct chromatin states, which assist coordinated gene regulation.
West, A., Ma, M.K-W., Adam G West, Heath, C., Carol Heath, Adam G. West, Meiji Kit-Wan Ma, Hair, A., Alan Hair   +8 more
core   +2 more sources