Results 61 to 70 of about 1,112,729 (199)
Transcriptional memory emerges from cooperative histone modifications [PDF]
, 2011 Background Transcriptional regulation in cells makes use of diverse mechanisms to ensure that functional states can be maintained and adapted to variable environments; among them are chromatin-related mechanisms.
Thimo Rohlf +4 more
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Histone modifications and the HtrA-like serine protease Nma111p regulate apoptosis in budding yeast [PDF]
, 2010 Histone modifications and the HtrA-like serine protease Nma111p regulate apoptosis in budding yeast David Walter, 2010, PhD Thesis, University of Basel Apoptosis is a form of programmed cell death that plays a central role in development and ...
Walter, David
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The role of histone modifications in leukemogenesis
Journal of Biosciences, 2020 Histone modifications play a critical role in coordinating accurate gene expression. Aside from genetic mutations which cause altered DNA sequence, it has become increasingly clear that aberrant post-translational modifications of histone tails are also associated with leukemogenesis.
Noah W, Birch, Ali, Shilatifard
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Chatting histone modifications in mammals [PDF]
Briefings in Functional Genomics, 2010 Eukaryotic chromatin can be highly dynamic and can continuously exchange between an open transcriptionally active conformation and a compacted silenced one. Post-translational modifications of histones have a pivotal role in regulating chromatin states, thus influencing all chromatin dependent processes.
A. Izzo, R. Schneider
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Epigenetics, 2020 DNA methylation and histone modifications are two major epigenetic marks in mammalian cells. Previous studies have revealed that these two mechanisms interact although a quantitative model of these is still lacking in mammalian cells.
Kai Fu +2 more
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Epigenetic modifications of histones in cancer [PDF]
Genome Biology, 2019 AbstractThe epigenetic modifications of histones are versatile marks that are intimately connected to development and disease pathogenesis including human cancers. In this review, we will discuss the many different types of histone modifications and the biological processes with which they are involved. Specifically, we review the enzymatic machineries
Zibo Zhao, Ali Shilatifard
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MAP kinases and histone modification [PDF]
Journal of Molecular Cell Biology, 2012 Signal transduction pathways alter the gene expression program in response to extracellular or intracellular cues. Mitogen-activated protein kinases (MAPKs) govern numerous cellular processes including cell growth, stress response, apoptosis, and differentiation.
Tamaki, Suganuma, Jerry L, Workman
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Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes
Nature Communications, 2020 Histone modification and deposition are key regulators of transcription. Here, Kraus et al. provide a quantitative histone acetylome for Trypanosoma brucei, identify histone modifications enriched at transcription start sites, and show how H4 and H2A.Z ...
Amelie J. Kraus +5 more
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The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation
Cellular & Molecular Biology Letters, 2022 Canonical Wnt/β-catenin signaling is a complex cell-communication mechanism that has a central role in the progression of various cancers. The cellular factors that participate in the regulation of this signaling are still not fully elucidated.
Hongjuan You +6 more
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