Results 31 to 40 of about 1,112,729 (199)

Computational study of associations between histone modification and protein-DNA binding in yeast genome by integrating diverse information

BMC Genomics, 2011
Background In parallel with the quick development of high-throughput technologies, in vivo (vitro) experiments for genome-wide identification of protein-DNA interactions have been developed.
Wang Junbai
doaj   +1 more source

Stage-specific histone modification profiles reveal global transitions in the Xenopus embryonic epigenome. [PDF]

, 2011
Vertebrate embryos are derived from a transitory pool of pluripotent cells. By the process of embryonic induction, these precursor cells are assigned to specific fates and differentiation programs.
Jose M. Arteaga-Salas, Edith Mentele, Ralph A. W. Rupp, Arteaga-Salas, Jose M., Tobias D Schneider, Schneider, Tobias D., Tobias D. Schneider, Rupp, Ralph A. W., Jose M Arteaga-Salas, Ralph A W Rupp, Imhof, Axel, Nicetto, Dario, Dario Nicetto, Robert David, Axel Imhof, Mentele, Edith, David, Robert   +16 more
core   +1 more source

HER2 low expression breast cancer subtyping and their correlation with prognosis and immune landscape based on the histone modification related genes

Scientific Reports, 2023
Human epidermal growth factor receptor 2 (HER2) plays an important role in diagnosis and treatment of breast cancer (BRCA). The histone modification has been found to be related to the progression of cancer.
Jia Li, Jingchun Yao, Liqiang Qi
doaj   +1 more source

Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription [PDF]

, 2014
Post-translational modifications of proteins have emerged as a major mechanism for regulating gene expression. However, our understanding of how histone modifications directly affect chromatin function remains limited.
Holzner, M. (M), Eleni Kallis, Holzner, M., Michaelis, J., Richter, F. (F) M. (M), Ryan, D. (D) P. (P), Feldmann, A. (A), Daniel P Ryan, Owen-Hughes, Tom; id_orcid, Kacem, S., Tropberger, Philipp, Di Cerbo, V., Bannister, A., Kallis, E. (E), Michaelis, Jens, Feldmann, A., Richter, Florian, Martin, Daujat, S. (Sylvain), Robert Schneider, Richter, F., Tropberger, P., Hoerner, Leslie, Richter, Florian Martin, Mittler, G. (G), Emilie Montellier, Di Cerbo, V. (V), Feil, Robert, Bannister, A. (A) J. (J), Vincenzo Di Cerbo, Ryan, D., Kallis, Eleni, Ryan, D. P., Di Cerbo, Vincenzo, Owen-Hughes, T. (T), Leslie Hoerner, Jens Michaelis, Kallis, E., Khochbin, S. (S), Saadi Khochbin, Schneider, Robert, Holzner, Monika, Monika Holzner, Feil, R. (R), Ryan, Daniel, P., Feldmann, Angelika, Tom Owen-Hughes, Owen-Hughes, T., Bannister, A. J., Feil, R., Mohn, F., Hoerner, L., Fabio Mohn, Richter, F. M., Montellier, E. (E), Mittler, G., Schuebeler, D., Montellier, Emilie, Mohn, F. (F), Tropberger, P. (P), Angelika Feldmann, Owen-Hughes, Tom, Kacem, Salim, Mittler, Gerhard, Daujat, Sylvain, Montellier, E., Schneider, R., Dirk Schuebeler, Schuebeler, D. (D), Bannister, Andrew J., Hoerner, L. (L), Khochbin, S., Schneider, R. (Robert), Schuebeler, Dirk, Salim Kacem, Philipp Tropberger, Mohn, Fabio, Florian Martin Richter, Kacem, S. (S), Sylvain Daujat, Ryan, Daniel P., Andrew J Bannister, Khochbin, Saadi, Gerhard Mittler, Michaelis, J. (J), Robert Feil, Daujat, S.   +85 more
core   +1 more source

Normal histone modifications on the inactive X chromosome in ICF and Rett syndrome cells: implications for methyl-CpG binding proteins

BMC Biology, 2004
Background In mammals, there is evidence suggesting that methyl-CpG binding proteins may play a significant role in histone modification through their association with modification complexes that can deacetylate and/or methylate nucleosomes in the ...
Canfield Theresa K, Luo Ping, Varadarajan Kartik R, Gartler Stanley M, Traynor Jeff, Francke Uta, Hansen R Scott   +6 more
doaj   +1 more source

The Histone Modifications of Neuronal Plasticity [PDF]

Neural Plasticity, 2021
Nucleosomes composed of histone octamer and DNA are the basic structural unit in the eukaryote chromosome. Under the stimulation of various factors, histones will undergo posttranslational modifications such as methylation, phosphorylation, acetylation, and ubiquitination, which change the three-dimensional structure of chromosomes and affect gene ...
Huixia Geng, Hongyang Chen, Haiying Wang, Lai Wang   +3 more
openaire   +3 more sources

Reconstruction of Histone Modification Network from Next-generation Sequencing Data [PDF]

, 2011
Post-translational modifications (PTMs) of histoneproteins play critical roles in establishing functionallyseparated domains on chromatin and regulating importantbiological processes, such as transcription.
Ngoc Tu Le, Tu Bao Ho, Ho, Tu Bao, Le, Ngoc Tu   +3 more
core   +1 more source

Histone modifications centric-regulation in osteogenic differentiation

Cell Death Discovery, 2021
Histone modification critically contributes to the epigenetic control of gene expression by changing the configuration of chromatin and modifying the access of transcription factors to gene promoters.
Kun Li, Jinxiang Han, Ziqiang Wang
doaj   +1 more source

ChIP-seq profiling of H3K4me3 and H3K27me3 in an invasive insect, Bactroceradorsalis

Frontiers in Genetics, 2023
Introduction: While it has been suggested that histone modifications can facilitate animal responses to rapidly changing environments, few studies have profiled whole-genome histone modification patterns in invasive species, leaving the regulatory ...
Yan Zhao, Juntao Hu, Jiajiao Wu, Zhihong Li   +3 more
doaj   +1 more source

Analysis of Jmjd6 cellular localization and testing for its involvement in histone demethylation. [PDF]

, 2010
Methylation of residues in histone tails is part of a network that regulates gene expression. JmjC domain containing proteins catalyze the oxidative removal of methyl groups on histone lysine residues.
Erck, C, Böttger, Angelika, Burrells Alison, Andreas Lengeling, Butler, Danica, Hahn, P., Erck, Christian, Wolf, A., Lengeling, A., Bottger, A., Jens Böse, Erck, C., Christopher J Schofield, Hahn, P, Wegener, Ivonne, Wegener Ivonne, Böse, Jens, Christian Erck, Angelika Böttger, Burrells, A, Ivonne Wegener, Butler, D, Butler Danica, Lengeling Andreas, Böse Jens, Burrells, A., Alexander Wolf, Hahn Phillip, Wolf, A, Bose, J., Lengeling, A, Erck Christian, Böttger Angelika, Danica Butler, Phillip Hahn, Butler, D., Wolf Alexander, Hahn, Phillip, Wolf, Alexander, Schofield, Christopher J, Alison Burrells, Schofield Christopher J., Böse, J, Lengeling, Andreas, Schofield, Christopher J., Wegener, I, Schofield, CJ, Wegener, I., Burrells, Alison, Schofield, Christopher, Böttger, A, Christopher J. Schofield   +51 more
core   +2 more sources