Results 31 to 40 of about 11,244 (122)

Diagnósticos, fármacos y mujeres internadas en un hospital neuropsiquiátrico

open access: yesRevista Estudos Feministas, 2023
El artículo sigue una perspectiva interseccional situada, e incorpora análisis desde la sociología del diagnóstico y los estudios sociales de los fármacos.
Eugenia Bianchi
doaj   +1 more source

Insights into the catalytic mechanism of formate dehydrogenases from different microbial sources

open access: yesThe FEBS Journal, EarlyView.
This integrated study combines experimental enzyme kinetics with QM/MM simulations to map the catalytic mechanisms of four formate dehydrogenases at the atomic level. This approach reveals the key determinants of catalytic efficiency and guides the rational design of biocatalysts for effective CO2 reduction—a crucial step towards sustainable ...
Laura Legnani   +8 more
wiley   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato   +3 more
wiley   +1 more source

Hit‐To‐Lead Optimization of a Pyridylpiperazine Class Against Malaria: Pharmacokinetic Profile and In Vivo Efficacy of Optimized Compounds

open access: yesChemMedChem, Volume 21, Issue 13, 14 July 2026.
Chemical optimization of a novel pyridylpiperazine class yields two promising antimalarial candidates with an exceptional balance of metabolic stability and solubility. These optimized leads significantly protect mice from cerebral malaria, reducing parasitic load by up to 91.7%.
Douglas Davison da Silva Oliveira   +8 more
wiley   +1 more source

Análise sensorial como ferramenta útil no desenvolvimento de cosméticos

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2012
Na avaliação da qualidade de cosméticos, é indiscutível o papel da análise sensorial como instrumento de medida científica, uma vez que não existe nenhum instrumento analítico capaz de substituir os sentidos humanos.
Vera Isaac   +3 more
doaj  

Recreational Drug Use at a Music Festival: A Dual Approach Using Hair Biomarkers Analysis and Participant Self‐Reported Drug Use

open access: yesDrug Testing and Analysis, Volume 18, Issue 7, Page 831-840, July 2026.
Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão   +4 more
wiley   +1 more source

Gender as a «niche»: the case of pharmaceutical advertising

open access: yesFeminismo/s, 2007
From a construction of scientific knowledge perspective, we consider the issues previously reviewed by other authors on how pharmaceutical companies commercialise their products to the point of bordering on the «generation» or «reinvention» of «illnesses»
Natalia Papí Gálvez   +2 more
doaj   +1 more source

O encontro com o mal. O jovem Nietzsche diante da doença (1844-1862)

open access: yesCadernos Nietzsche, 2020
Resumo Este artigo examina um período muito breve da juventude de Nietsche, de seu nascimento a 1862. Durante estes anos Nietzsche descobre progressivamente que o mundo encantado ao interno do qual ele nascera, protegido e seguro, não é imune ao mal e às
Simone Zacchini
doaj   +1 more source

Revisión sistemática de la epigenética y sus aplicaciones en salud

open access: yesRevista GICOS, 2022
El auge de la investigación en el campo epigenético se debe a las aplicaciones en investigación y desarrollo de nuevas estrategias terapéuticas basadas en la identificación de dianas moleculares, donde las modificaciones epigenéticas juegan un papel ...
María Solís
doaj   +1 more source

Pre‐Treatment Serum Albumin Concentration Predicts Clinical Benefit of Long‐Term Albumin in Patients With Cirrhosis and Ascites

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 6, July 2026.
ABSTRACT Background and Aims The benefit of long‐term albumin (LTA) in improving survival and reducing complications in patients with cirrhosis and ascites is not consistently observed across studies, possibly reflecting differences in patient populations and treatment regimens.
Enrico Pompili   +21 more
wiley   +1 more source

Home - About - Disclaimer - Privacy