Results 21 to 30 of about 373,254 (241)
De fã para fã: as traduções de Chrono Trigger
Scientia Traductionis, 2014 This paper was written under the umbrella of Translation Studies in general and of fan translation and game translation in particular. Through the analysis of the translation into Brazilian Portguese made by fans of the game Chrono Trigger it was possible to show how fans may get results similar to those achieved by localization professionals. In order
openaire +2 more sources
New superconformal multiplets and higher derivative invariants in six dimensions
Nuclear Physics B, 2017 Within the framework of six-dimensional N=(1,0) conformal supergravity, we introduce new off-shell multiplets Oâ(n), where n=3,4,â¦, and use them to construct higher-rank extensions of the linear multiplet action.
Sergei M. Kuzenko +2 more
doaj +1 more source
Exact solution of matricial Φ23 quantum field theory
Nuclear Physics B, 2017 We apply a recently developed method to exactly solve the Φ3 matrix model with covariance of a two-dimensional theory, also known as regularised Kontsevich model. Its correlation functions collectively describe graphs on a multi-punctured 2-sphere.
Harald Grosse +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2016 O Brasil foi um dos primeiros paÃses do Sul Global a incluir em suas polÃticas de saúde pública robustas medidas de controle contra a epidemia de HIV/Aids.
Carla Cristina de Freitas da Silveira +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Revista Portuguesa de Pneumologia, 2009 Resumo: A alfa-1 antitripsina (AAT) é sintetizada pelo fÃga-do, com uma semivida plasmática de 4-5 dias. Apresenta acção inibidora das proteases, com particular afinidade para a elastase dos neutrófilos.
Carla Alves Costa, Cristina Santos
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source