Results 41 to 50 of about 32,762 (226)

Excessive food intake, obesity and inflammation process in Zucker fa/fa rat pancreatic islets. [PDF]

PLoS ONE, 2011
Inappropriate food intake-related obesity and more importantly, visceral adiposity, are major risk factors for the onset of type 2 diabetes. Evidence is emerging that nutriment-induced β-cell dysfunction could be related to indirect induction of a state ...
Myriam Chentouf, Gregor Dubois, Céline Jahannaut, Françoise Castex, Anne Dominique Lajoix, René Gross, Sylvie Peraldi-Roux   +6 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

DGAT inhibition at the post‐absorptive phase reduces plasma FA by increasing FA oxidation

EMBO Molecular Medicine, 2023
Graphical Abstract In this Correspondence, A. Sharma & C. Wolfrum report that DGAT1/2 pharmacological inhibition at post‐absorptive phase in mice leads to increased fatty acid oxidation and reduced plasma fatty acid levels, which could open new ...
Anand Kumar Sharma, Christian Wolfrum
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Review of supplemental oxygen and respiratory support for paediatric emergency care in sub-Saharan Africa

African Journal of Emergency Medicine, 2017
Introduction: In African countries, respiratory infections and severe sepsis are common causes of respiratory failure and mortality in children under five years of age.
Andreas Hansmann, Brenda May Morrow, Hans-Joerg Lang   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Characteristics and economic burden of frequent attenders with medically unexplained symptoms in primary care in Israel

European Journal of General Practice, 2021
Background Frequent Attenders with Medically Unexplained Symptoms (FA/MUS) are common in primary care, though challenging to identify and treat. Objectives This study sought to compare FA/MUS to FA with organic illnesses (FA/OI) and the general clinic ...
Oded Hammerman, Daniel Halperin, Daniel Tsalihin, Dan Greenberg, Talma Kushnir, Yacov Ezra   +5 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

fa [PDF]

پژوهش در نظام‌های آموزشی, 2011
هدف تحقیق یافتن به سؤالات زیر بوده است: الف ) در حال حاضر دانشگاه علامه طباطبائی از چهامکانات و وسایل و تجهیزاتی جهت آموزش دانشجویان برخوردار است؟ ب) برای برگزاری دوره ها یآموزشی از راه آموزش الکترونیکی در دانشگاه علامه طباطبائی چه امکانات و تجهیزاتی ...
mo ja, da na
doaj  

Fã-ativismo no Twitter: comunidades online de fãs de esporte e a campanha #ForaRicardoTeixeira

C-Legenda - Revista do Programa de Pós-graduação em Cinema e Audiovisual, 2013
Este artigo discute especificamente um tipo de prática da cultura fã, o que estou chamando de fã-ativismo. Fã-ativismo é um tópico que historicamente recebeu pouca atenção de pesquisadores da área de estudos de fandom. Aqui, analiso a campanha #ForaRicardoTeixeira a partir de uma amostra de 15 mil tweets postados à época da renúncia do dirigente do ...
openaire   +1 more source