Results 41 to 50 of about 373,254 (241)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

DGAT inhibition at the post‐absorptive phase reduces plasma FA by increasing FA oxidation

EMBO Molecular Medicine, 2023
Graphical Abstract In this Correspondence, A. Sharma & C. Wolfrum report that DGAT1/2 pharmacological inhibition at post‐absorptive phase in mice leads to increased fatty acid oxidation and reduced plasma fatty acid levels, which could open new ...
Anand Kumar Sharma, Christian Wolfrum
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Review of supplemental oxygen and respiratory support for paediatric emergency care in sub-Saharan Africa

African Journal of Emergency Medicine, 2017
Introduction: In African countries, respiratory infections and severe sepsis are common causes of respiratory failure and mortality in children under five years of age.
Andreas Hansmann, Brenda May Morrow, Hans-Joerg Lang   +2 more
doaj   +1 more source

Characteristics and economic burden of frequent attenders with medically unexplained symptoms in primary care in Israel

European Journal of General Practice, 2021
Background Frequent Attenders with Medically Unexplained Symptoms (FA/MUS) are common in primary care, though challenging to identify and treat. Objectives This study sought to compare FA/MUS to FA with organic illnesses (FA/OI) and the general clinic ...
Oded Hammerman, Daniel Halperin, Daniel Tsalihin, Dan Greenberg, Talma Kushnir, Yacov Ezra   +5 more
doaj   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Fã-ativismo no Twitter: comunidades online de fãs de esporte e a campanha #ForaRicardoTeixeira

C-Legenda - Revista do Programa de Pós-graduação em Cinema e Audiovisual, 2013
Este artigo discute especificamente um tipo de prática da cultura fã, o que estou chamando de fã-ativismo. Fã-ativismo é um tópico que historicamente recebeu pouca atenção de pesquisadores da área de estudos de fandom. Aqui, analiso a campanha #ForaRicardoTeixeira a partir de uma amostra de 15 mil tweets postados à época da renúncia do dirigente do ...
openaire   +1 more source

A vida organizada dos fãs de Harry Potter [PDF]

Organizações & Sociedade, 2018
Resumo A saga Harry Potter se tornou um dos principais produtos da indústria do entretenimento da história, tendo um enorme impacto cultural e sendo emblemática, com uma geração de fãs denominados potterheads. Surgiu em um contexto de globalização e de grande desenvolvimento tecnológico, que afetou sobremaneira os modos de sociabilidade.
Costa, Flávia Zimmerle da Nóbrega, Leão, André Luiz Maranhão de Souza   +1 more
openaire   +3 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

fa [PDF]

پژوهش در نظام‌های آموزشی, 2011
هدف تحقیق یافتن به سؤالات زیر بوده است: الف ) در حال حاضر دانشگاه علامه طباطبائی از چهامکانات و وسایل و تجهیزاتی جهت آموزش دانشجویان برخوردار است؟ ب) برای برگزاری دوره ها یآموزشی از راه آموزش الکترونیکی در دانشگاه علامه طباطبائی چه امکانات و تجهیزاتی ...
mo ja, da na
doaj