Results 151 to 160 of about 158,736 (197)

Fatty Acids in Cancer Therapy: Chemical Conjugates, Nanocarriers, and Therapeutic Opportunities. [PDF]

Molecules
Antal G, Pașcalău NA, Atyim E, Bătrîna O, Șoica C, Mioc M, Tandafirescu C, Mioc A.   +7 more
europepmc   +1 more source

Incomplete Spoiling Correction for 3D T1$$ {T}_1 $$ Mapping

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Assess the impact of incomplete spoiling and spatial saturation on T1$$ {T}_1 $$ mapping using the variable flip angle (VFA) spoiled gradient recalled echo sequence (SPGR). Develop a correction for incomplete spoiling that results in an accurate estimate of T1$$ {T}_1 $$, essential for quantitative MRI applications.
Gabriela Belsley, Damian J. Tyler, Matthew D. Robson, Elizabeth M. Tunnicliffe   +3 more
wiley   +1 more source

Symptom burden, lung function, exercise tolerance and inflammation in patients post COVID-19: results from the prospective COVID-19 Chronic Morbidity (CCHROMO) study. [PDF]

BMC Pulm Med
Bellinghausen C, Grünewaldt A, Azem T, Lask C, Du W, Seeger A, Herrmann E, Schubert R, Hafner J, Vehreschild MJGT, Appel TM, Rohde G.   +11 more
europepmc   +1 more source

Deciphering the Inflammatory Network in Pediatric Recurrent Tonsillitis: The Role of TRAF6, IRAK1, and miR‐146a‐5p

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To investigate the role of TNF receptor‐associated factor 6 (TRAF6), interleukin 1 receptor‐associated kinase 1 (IRAK1), and miR‐146a‐5p expression levels in the pathogenesis of recurrent tonsillitis. Study Design Case‐control study. Setting The study was conducted at the Department of Otorhinolaryngology, Muğla Training and Research
Ömer Faruk Güzel, Çilem Özdemir, Tuba Edgünlü, Ozan Gökdoğan   +3 more
wiley   +1 more source

Correction of hypoxemia and hypoglycemia restores muscle mitochondrial respiration and remodels mitochondrial proteome in growth-restricted sheep fetuses. [PDF]

Am J Physiol Endocrinol Metab
Zhao W, Chrisenberry DB, Varela M, Luna-Ramirez RI, Anderson MJ, Langlais PR, Brown LD, Limesand SW.   +7 more
europepmc   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source

Burden of novel and ultra-rare missense variants in the NF-κB pathway genes associated to Ménière's disease. [PDF]

Front Immunol
Cruz-Granados P, Rivero de Jesus V, Soto-Varela A, Gonzalez-Aguado R, Lopez-Escamez JA.   +4 more
europepmc   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Comparative analysis of milk and brain fatty acids reveals human-specific signatures in brain development. [PDF]

Commun Biol
Mitina A, Wang Y, Mair W, Vanyushkina A, Anikanov N, Efimova O, Guo S, Mazin P, Khaitovich P.   +8 more
europepmc   +1 more source

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

Precision Radiation Oncology, EarlyView.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu, Yang Zhang, Zuomin Wang, Zongjuan Li, Shisuo Du   +4 more
wiley   +1 more source