Results 151 to 160 of about 165,720 (231)

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

A Buried Sulfonate Molecular Bridge for Synchronous Charge Transport and Defect Passivation in High-Performance Perovskite Solar Cells. [PDF]

Nanomicro Lett
Zha L, Ding W, Gao Y, Wu X, Song T, Li C, Duan C, Lu X, Cai G, Zhang S.   +9 more
europepmc   +1 more source

How much does the reduced electroencephalographic montage matter for seizure detection? A large‐cohort simulation study

Epilepsia, EarlyView.
Abstract Objective Subscalp electroencephalographic (EEG) systems with few channels have emerged as promising solutions for ultra‐long‐term seizure monitoring, but the impact of montage configuration on automated seizure detection is unclear. We compared automated detection performance between full‐scalp and simulated reduced montages approximating ...
Joe Kojima, Haoer Shi, Svanik Jaikumar, William K. S. Ojemann, Carlos Aguila, Juri Kim, Taneeta Mindy Ganguly, Brian Litt, Erin C. Conrad   +8 more
wiley   +1 more source

Multicenter External Validation of an AI-Based Funduscopic Carotid Atherosclerosis Score and Assessment of Its Association With Coronary Artery Calcification: External Validation Study. [PDF]

JMIR Med Inform
Han C, Chang J, Kim J, Lee H, Kim KH, Cho S, Kwon H, Kim S, Park SM.   +8 more
europepmc   +1 more source

Detection of focal impaired awareness seizures using a biometric shirt

Epilepsia Open, EarlyView.
Abstract Objective In recent years, seizure detection using wearable technology has gained significant attention in research. Most studies, however, have focused on detecting generalized or focal to bilateral tonic–clonic seizures. This study evaluates the feasibility of using a biometric shirt to detect focal impaired awareness seizures (FIAS) by ...
Jérôme St‐Jean, Oumayma Gharbi, Dènahin Hinnoutondji Toffa, Thi Phuoc Yen Tran, Manon Robert, Dang Khoa Nguyen, Elie Bou Assi   +6 more
wiley   +1 more source

Modulation of Host Cell Death Signaling Platforms by <i>Plasmodium falciparum</i>: Implications for Eryptosis Regulation and Parasite Survival. [PDF]

Cells
Solís-Castillero L, Correa R, Alves-Rosa MF, Spadafora C.   +3 more
europepmc   +1 more source

LXRα and PPARα Mediated Hepatic Lipid Metabolic Disruption Induced by the UV Filter EHMC in 2D and 3D HepaRG Cell Models

Food Safety and Health, EarlyView.
Dietary UV filter EHMC induces hepatic steatosis in HepaRG cells at noncytotoxic concentrations. Mechanistically, EHMC binds nuclear receptors (LXRα, PPARα), upregulating SREBP‐1 to accelerate fatty acid synthesis. These findings highlight the potential metabolic toxicity of widespread EHMC exposure through food sources.
Shanglin Yang, Na Li, Yingnan Han, Mei Ma   +3 more
wiley   +1 more source

Fatty Acid Deaggregation and Extraction from Vesicles by Serum Albumin Proceeds Via a Dock-and-Load Mechanism. [PDF]

J Phys Chem Lett
Michler S, Schreiber N, Saluja TK, Chan WS, Knösche MG, Hinderberger D.   +5 more
europepmc   +1 more source

4-2 VHL-Recruiting PROTAC Inhibits the Growth and Migration of Triple Negative Breast Cancer Cells by Triggering Pyroptosis Through Fas-Mediated IL-17 Signaling. [PDF]

Drug Dev Res
Wang Q, Huang Q, Ou H, Huang T, He Y, Li P.   +5 more
europepmc   +1 more source

Short-Course Subcutaneous Immunotherapy With Mannan-Conjugated Birch Pollen Allergoids: Consistent Clinical and Immunological Improvements. [PDF]

Clin Transl Allergy
Raskopf E, Passamera S, Klimek L, Pfaar O, Neuhof C, Rybachuk A, Katzke N, Sahin H, Allekotte S, Mösges R, Day L, Subiza JL, Casanovas M, Cuevas M, Del Pozo S.   +14 more
europepmc   +1 more source