Results 161 to 170 of about 165,720 (231)

Spontaneous lymphoproliferation differentiates two groups of HTLV-1 asymptomatic carriers: with and without high cell proliferation and death. [PDF]

Immunol Res
de Souza Porto M, Mitiko T, Folgosi V, Vasconcelos D, Domingues M, Haziot M, Smid J, Marcusso R, Nukui Y, Oliveira ACP, Assone T, Casseb J, Benard G.   +12 more
europepmc   +1 more source

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

iMeta, EarlyView.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen, Xiaoling Wang, Xiang Liu, Kui Dong, Yanying Feng, Min Yuan, Shiyi Wang, Fangfang Fan, Yong Tian, Zhiming Kang, Xiushuai Du, Chaolu Hasi, Hong Lu, Wei Guan, Xu Chen, Mengyu Cheng, Wei Wei, Nan Guo, Zhiguo Liu, Xiaotong Qiu, Yiwei Shi, Kun Xiao, Yi Wang, Zhenjun Li   +23 more
wiley   +1 more source

Higher Plasma Saturated and Omega-6 Fatty Acids Associated with Cholesterol Homeostasis and Gut Microbiota in Pediatric Type 2 Diabetes and Metabolic Syndrome. [PDF]

Comput Struct Biotechnol J
Mora-Godínez S, Marín-Obispo LM, Mellado-Negrete A, de la Garza AL, Tamez-Rivera O, Navarro-Guerra M, Telles-Ramírez B, Martínez-Ledesma E, Castaño-Moreno E, Senés-Guerrero C, Rodríguez-Sánchez D, García-Rivas G, Castillo EC, Rodríguez-Gutiérrez NA, Elizondo-Montemayor L, Hernández-Brenes C.   +15 more
europepmc   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source

Quantitative Three-Dimensional Characterization of Facial Dysmorphism in Self-Identified African-American Individuals With Prenatal Alcohol Exposure. [PDF]

Alcohol Clin Exp Res (Hoboken)
Li Q, Mozaffarian Z, Moghaddasi H, Coles CD, Kable JA, Mattson SN, Wozniak JR, Jones KL, Del Campo M, Wetherill L, Suttie M, CIFASD Consortium.   +11 more
europepmc   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Beyond Fatigue: The Fatigue Assessment Scale as a Potential Indicator of Long COVID Severity. [PDF]

J Clin Med
Del Duca G, Franco M, Talamanca L, Antinori A, Camici M.   +4 more
europepmc   +1 more source

Investigating Associations Between Signal Intensity of Silent MR Angiography and Hemodynamic Information From 4D Flow MRI in Brain Arteriovenous Malformation

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Whether signal intensity (SI) on Silent MRA reflects hemodynamics in brain arteriovenous malformations (BAVMs) is unclear. Objectives To evaluate the relationship between Silent MRA SI and 4D flow‐derived hemodynamic parameters and examine whether Silent MRA‐based metrics are associated with symptomatic hemorrhage in BAVM.
Linshu Yang, Xiaosheng Meng, Haining Wei, Xiaoqian Li, Yang Yu, Qin Qin, Dan Zhu, Tao Hong, Hongqi Zhang, Rui Li, Jiaxing Yu, Chunxue Wu, Jie Lu   +12 more
wiley   +1 more source

Fatigue after pulmonary embolism-prevalence and predictors. [PDF]

Front Cardiovasc Med
Schmitz M, Fischer S, Berghaus TM, Naumann M, Linseisen J, Meisinger C, Kirchberger I.   +6 more
europepmc   +1 more source

Pharmacokinetics and Pharmacodynamics of a Single Oral Dose of Ascelia‐Manganese‐Based MRI Contrast Agent (ACE‐MBCA) in Adult Subjects With and Without Hepatic Impairment

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Orally administered Ascelia‐manganese‐based contrast agent (ACE‐MBCA) is used for liver MRI, but its feasibility in patients with hepatic dysfunction remains unknown. Purpose To investigate the pharmacokinetics (PK), pharmacodynamics, and safety of ACE‐MBCA in subjects without/with hepatic impairment.
Amit G. Singal, Eric Lawitz, Andreas Norlin, Nadilka Hettiarachchige, Thomas Bengtsson, Bachir Taouli   +5 more
wiley   +1 more source