Results 171 to 180 of about 158,736 (197)

Do Sovereign‐Environmental, Social and Governance (S‐ESG) Commitments Promote Financial Inclusion?

Thunderbird International Business Review, EarlyView.
ABSTRACT Given the need to respect humanity, the environment, and society, and the progressive development of social responsibility, environmental, social and governance (ESG) commitments and the need for ethical and sustainable finance, this paper aims to examine the impact of sovereign ESG on financial inclusion (FI).
Inès Gharbi, Simplice A. Asongu, Aïda Kammoun   +2 more
wiley   +1 more source

Fusion protein-mediated costimulation in engineered T cells: from intrinsic signaling to tumor microenvironment rewiring. [PDF]

Front Immunol
Toumi R, Guenette SJ, Oda SK.
europepmc   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Effects of Nacubactam and Its Metabolites on QTc Interval: A Pooled Analysis of Two Randomized Phase 1 Studies. [PDF]

Clin Transl Sci
Morita J, McKendrick S, Kumagai Y.
europepmc   +1 more source

Avoiding pitfalls when modelling ligands in macromolecular crystallography

Acta Crystallographica Section D, EarlyView.
Flawed protein–ligand X‐ray structures can misdirect drug discovery based on PDB‐deposited models. This review uses publicly available PDB examples to highlight potential pitfalls, from absent ligands to incorrect chemistry, and presents a practical validation approach to improve model reliability.The determination of protein–ligand complex structures ...
Oliver S. Smart, Andrew Sharff, Claus Flensburg, Clemens Vonrhein, Gérard Bricogne   +4 more
wiley   +1 more source

Self-Assembly of Amyloid Fibrils into Fibrillar Superstructure Monitored with Thioflavin T. [PDF]

Biomolecules
Bushra N, Hull T, Fakhre D, Muschol M.
europepmc   +1 more source

Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms

The Journal of Dermatology, EarlyView.
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du, Anika Jallorina, Toru Yoshino, Lingyu Bao, Han Bao, Victor Chang, Henry K. Wong, Derek V. Chan, Stephen K. Richardson, Mary F. Lee‐Wong   +9 more
wiley   +1 more source

Docetaxel enhances Vβ-directed T-cell activation and antitumor immunity mediated by a bifunctional TCR agonist in breast and prostate cancer models. [PDF]

Front Immunol
Lee JK, Fabian KP, Santiago-Sanchez GS, Rosato F, Padget MR, Lee C, Su Z, Moisan J, Katragadda M, Schlom J, Gulley JL, Bayliffe A, Hodge JW.   +12 more
europepmc   +1 more source

Real Effects of Subjectivity in Measuring Fair Values

Journal of Accounting Research, EarlyView.
ABSTRACT This study examines how the subjectivity in measuring fair values of assets without readily observable market prices affects investment efficiency and shareholder value. When fair values are objective measures of asset value, they facilitate efficient investment decisions that align with shareholder interests.
VERENA BRAUN, ROBERT F. GÖX, FELIX P. NIGGEMANN, ULRICH SCHÄFER   +3 more
wiley   +1 more source

Regulation of reticular adhesions by KANK2 and talin2 in two melanoma cell lines. [PDF]

Cell Commun Signal
Rac A, Lončarić M, Stojanović N, Fatima M, Rešetar M, Hršak D, Humphries JD, Humphries MJ, Ambriović-Ristov A.   +8 more
europepmc   +1 more source