Results 31 to 40 of about 173,176 (244)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden. [PDF]

PLoS ONE, 2010
Fas, a member of the tumor necrosis family, is responsible for initiating the apoptotic pathway when bound to its ligand, Fas-L. Defects in the Fas-mediated apoptotic pathway have been reported in colorectal cancer.In the present study, a variant of the ...
Hector Guillen-Ahlers, Mark A Suckow, Francis J Castellino, Victoria A Ploplis   +3 more
doaj   +1 more source

De on tango street a tango nas ruas: explorando a fanfiction e a autotradução na tliteratura da geração da internet [PDF]

, 2011
Tese de Mestrado Tradução e Interpretação Especializadas Joana Santos Nazaré Orientador: Professora Doutora Manuela Veloso Instituto de Contabilidade e ...
Nazaré, Joana Santos
core  

"Bitches Ain't Gonna Hunt No Ghosts": Totemic Nostalgia, Toxic Fandom and the Ghostbusters Platonic [PDF]

, 2017
In March 2016, the trailer for Paul Feig’s Ghostbusters reboot debuted online and suffered the unfortunate accolade of being the most disliked trailer in YouTube history.
Proctor, William
core   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

An Efficient Algorithm for Zeros of Bounded Generalized Ghi-Quasi-Accretive Maps

The Proceedings of the Nigerian Academy of Science, 2013
This is a research announcement of the following result. Let E be a real normed linear space in which the single-valued normalized duality map is Holder continuous on balls and let A: E → E be a bounded generalized Φ-quasi-accretive map.
C. E. Chidume FAS, C. O. Chidume
doaj   +1 more source

Updating the fatty acid profiles of retail bovine milk in China based on an improved GC-MS method: implications for nutrition

Frontiers in Nutrition, 2023
The importance of food components to potential benefits and risks to human health is gradually being consumer awareness. Milk is an important part of the lipid content of the human diet, and there are few detailed reports on the fatty acid (FA) profiles ...
Meiqing Chen, Meiqing Chen, Fengen Wang, Xufang Wu, Xufang Wu, Boxue Si, Boxue Si, Junyu Pan, Junyu Pan, Nan Zheng, Nan Zheng, Yangdong Zhang, Yangdong Zhang, Jiaqi Wang, Jiaqi Wang   +14 more
doaj   +1 more source

Inbound Marketing: análise do lançamento de um produto digital [PDF]

, 2016
O trabalho tem como objetivo analisar o lançamento do Curso On-line de Cavaquinho do integrante do Grupo Sambô, Julio Fejuca. A pesquisa apresenta os resultados obtidos com a prática do Inbound Marketing aliada às atividades exercidas pelo profissional ...
Zart, Douglas Cardoso
core  

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source