Results 51 to 60 of about 165,720 (231)

Transmídia na teleficção brasileira: produtos e possibilidades

Comunicação & Educação, 2014
A resenha traça um panorama da obra Estratégias de transmidiação na ficção televisiva brasileira1, que se apresenta como resultado das pesquisas desenvolvidas em 2012 e 2013 pela equipe de investigadores da rede Obitel-Brasil.
Silvia Gois Dantas
doaj  

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

Advanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao, Lingling Zhang, Yue Wen, Lianghui Cheng, Sidan Tian, Fanling Meng, Liang Luo   +6 more
wiley   +1 more source

Nestedness in forest mammals is dependent on area but not on matrix type and sample size: an analysis on different fragmented landscapes

Brazilian Journal of Biology
Nestedness, the pattern in which the species of a species-poor community are a subset of species-rich communities, can provide information regarding species order of extinction, which is vital knowledge for conservation biology.
JFS. Menezes, FAS. Fernandez
doaj   +1 more source

Performance, investimento afetivo e disputa simbólica: a dinâmica da comunidade de fãs do grupo Backstreet Boys [PDF]

, 2010
Fãs são conhecidos por atitudes extremas na tentativa de demonstrar admiração ou para chegar perto do ídolo. Embora muito desta visão permaneça até hoje no senso comum, com a expansão dos Estudos Culturais nos EUA e Inglaterra, a validade do discurso ...
Santos, Patrícia Matos dos
core  

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Beyond photoaging: additional factors involved in the process of skin aging

Clinical, Cosmetic and Investigational Dermatology, 2018
Flavia Alvim Sant’Anna Addor MEDCIN Research, Private Clinical Research Center, Osasco, São Paulo, Brazil Abstract: Studies assessing the impact of extrinsic factors on skin aging have increased during the last with the increase in life ...
Addor FAS
doaj  

Dynamic fluctuations provide the basis of a conformational switch mechanism in apo cyclic AMP receptor protein. [PDF]

PLoS Computational Biology, 2013
Escherichia coli cyclic AMP Receptor Protein (CRP) undergoes conformational changes with cAMP binding and allosterically promotes CRP to bind specifically to the DNA.
Burcu Aykaç Fas, Yusuf Tutar, Türkan Haliloğlu   +2 more
doaj   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

Ficção televisiva brasileira e fãs online: mapeamentos e investigações

Comunicação & Educação, 2016
O presente texto apresenta uma síntese da obra Por uma teoria de fãs da ficção televisiva brasileira[1], resultado de dez pesquisas colaborativas desenvolvidas entre 2014 e 2015 pela equipe de investigadores da rede Obitel Brasil.
Lucas Martins Néia
doaj  

The extracellular matrix, p53 and estrogen compete to regulate cell-surface Fas/Apo-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors, and reciprocally, Fas-ligand modifies estrogen control of cell-cycle proteins

BMC Neuroscience, 2004
Background Apoptosis is important for normal cerebral cortical development. We previously showed that the Fas suicide receptor was expressed within the developing cerebral cortex, and that in vitro Fas activation resulted in caspase-dependent death ...
Newman Joseph M, Wade Stephen B, Santillano Daniel R, Cheema Zulfiqar F, Miranda Rajesh C   +4 more
doaj   +1 more source